SALAS, GIMENA; LITTA, ALEN A.; MEDEOT, ANABELA CAROLINA; SCHUCK, VIRGINIA SOLEDAD; ANDERMATTEN, ROMINA B.; MISZCZUK, GISEL S.; CIRIACI, NADIA; RAZORI, MARÍA VALERIA; BAROSSO, ISMAEL R.; SÁNCHEZ POZZI, ENRIQUE J; ROMA, MARCELO G; BASIGLIO, CECILIA L; CROCENZI, FERNANDO A.

NADPH oxidase-generated reactive oxygen species are involved in estradiol 17ß-D-glucuronide-induced cholestasis

Biochimie; Lugar: Londres; Año: 2024 vol. 223 p. 41 - 53

BASIGLIO, CECILIA L.; CROCENZI, FERNANDO A.; SÁNCHEZ POZZI, ENRIQUE JUAN; ROMA, MARCELO GABRIEL

Oxidative stress and localization status of hepatocellular transporters: Impact on bile secretion and role of signaling pathways

ANTIOXIDANTS & REDOX SIGNALING; Año: 2021 vol. 35 p. 808 - 831

MISZCZUK, GISEL S.; BANALES, JESUS M.; ZUCCHETTI, ANDRÉS E.; PISANI, GERARDO B.; BOAGLIO, ANDREA C.; SAEZ, ELENA; MEDINA, JUAN F.; ROMA, MARCELO G.; CROCENZI, FERNANDO A.

Adaptive downregulation of Cl-/HCO3- exchange activity in rat hepatocytes under experimental obstructive cholestasis

PLOS ONE; Año: 2019 vol. 14

ROMA, MARCELO G.; BAROSSO, ISMAEL R.; MISZCZUK, GISEL S.; CROCENZI, FERNANDO A.*; POZZI, ENRIQUE J SÁNCHEZ*

Dynamic Localization of Hepatocellular Transporters: Role in Biliary Excretion and Impairment in Cholestasis

Current medicinal chemistry; Año: 2019 vol. 26 p. 1113 - 1154

CIRIACI, NADIA; ANDERMATTEN, ROMINA BELÉN; RAZORI, MARÍA VALERIA; SCHUCK, VIRGINIA SOLEDAD; MISZCZUK, GISEL SABRINA; MEDEOT, ANABELA CAROLINA; CROCENZI, FERNANDO ARIEL; ROMA, MARCELO GABRIEL; BAROSSO, ISMAEL RICARDO; RUIZ, MARÍA LAURA; SÁNCHEZ POZZI, ENRIQUE JUAN

Role of ERK1/2 in TNFα-induced internalization of Abcc2 in rat hepatocyte couplets

BIOCHEMICAL PHARMACOLOGY; Año: 2019 vol. 164 p. 311 - 320

ANDERMATTEN, ROMINA BELÉN; CIRIACI, NADIA; SCHUCK, VIRGINIA SOLEDAD; DI SIERVI, NICOLÁS; RAZORI, MARÍA VALERIA; MISZCZUK, GISEL SABRINA; MEDEOT, ANABELA CAROLINA; DAVIO, CARLOS ALBERTO; CROCENZI, FERNANDO ARIEL; ROMA, MARCELO GABRIEL; BAROSSO, ISMAEL RICARDO; SÁNCHEZ POZZI, ENRIQUE JUAN

Sphingosine 1-phosphate receptor 2/adenylyl cyclase/protein kinase A pathway is involved in taurolithocholate-induced internalization of Abcc2 in rats

ARCHIVES OF TOXICOLOGY.; Lugar: Berlin; Año: 2019 vol. 93 p. 2279 - 2294

BAROSSO, ISMAEL R.; MISZCZUK, GISEL S.; CIRIACI, NADIA; ANDERMATTEN, ROMINA B.; MAIDAGAN, PAULA M.; RAZORI, VALERIA; TABORDA, DIEGO R.; ROMA, MARCELO G.; CROCENZI, FERNANDO A.; SÁNCHEZ POZZI, ENRIQUE J.

Activation of insulin-like growth factor 1 receptor participates downstream of GPR30 in estradiol-17β-d-glucuronide-induced cholestasis in rats

ARCHIVES OF TOXICOLOGY.; Año: 2018 vol. 92 p. 729 - 744

MISZCZUK, GISEL S.; BAROSSO, ISMAEL R.; LAROCCA, MARÍA CECILIA; MARRONE, JULIETA; MARINELLI, RAÚL A.; BOAGLIO, ANDREA C.; SÁNCHEZ POZZI, ENRIQUE J.; ROMA, MARCELO G.; CROCENZI, FERNANDO A.

Mechanisms of canalicular transporter endocytosis in the cholestatic rat liver

BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE; Lugar: Amsterdam; Año: 2018 vol. 1864 p. 1072 - 1085

LOOS, JULIA A.; DÁVILA, VALERIA A.; RODRÍGUEZ RODRÍGUES, CHRISTIAN; PETRIGH, ROMINA; ZOPPI, JORGE A.; CROCENZI, FERNANDO A.; CUMINO, ANDREA C.

Metformin exhibits preventive and therapeutic efficacy against experimental cystic echinococcosis

PLOS NEGLECTED TROPICAL DISEASES; Lugar: San Francisco; Año: 2017 vol. 11

BAROSSO, ISMAEL R.; ZUCCHETTI, ANDRéS ERNESTO; MISZCZUK, GISEL SABRINA; BOAGLIO, ANDREA C; TABORDA, DIEGO; ROMA, MARCELO G; CROCENZI, FERNANDO A.; SáNCHEZ POZZI, ENRIQUE J

EGFR participates downstream of ERα in estradiol-17β-d-glucuronide-induced impairment of Abcc2 function in isolated rat hepatocyte couplets

ARCHIVES OF TOXICOLOGY.; Lugar: Berlin; Año: 2016 vol. 90 p. 891 - 903

MISZCZUK, GISEL SABRINA; BAROSSO, ISMAEL R.; ZUCCHETTI, ANDRéS ERNESTO; BOAGLIO, ANDREA C; PELLEGRINO, JOSé M; SáNCHEZ POZZI, ENRIQUE J; ROMA, MARCELO G; CROCENZI, FERNANDO A.

Sandwich-cultured rat hepatocytes as an in vitro model to study canalicular transport alterations in cholestasis

ARCHIVES OF TOXICOLOGY.; Lugar: Berlin; Año: 2015 vol. 89 p. 979 - 990

ZUCCHETTI, ANDRÉS ERNESTO; BAROSSO, ISMAEL R.; BOAGLIO, ANDREA C; BASIGLIO, CECILIA L; MISZCZUK, GISEL SABRINA; LAROCCA, M CECILIA; RUIZ, MARÍA LAURA; DAVIO, CARLOS; ROMA, MARCELO G; CROCENZI, FERNANDO A; SÁNCHEZ POZZI, ENRIQUE J

G-Protein-Coupled Receptor 30/Adenylyl Cyclase/ Protein Kinase A Pathway Is Involved in Estradiol 17ß-D-Glucuronide-Induced Cholestasis

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2014 vol. 59 p. 1016 - 1029

ZUCCHETTI, ANDRÉS ERNESTO; BAROSSO, ISMAEL R.; BOAGLIO, ANDREA C; LUQUITA, MARCELO G.; ROMA, MARCELO G.; CROCENZI, FERNANDO A.; SÁNCHEZ POZZI, ENRIQUE J.

Hormonal Modulation of Hepatic cAMP Prevents Estradiol 17β-D-Glucuronide-Induced Cholestasis in Perfused Rat Liver

DIGESTIVE DISEASE AND SCIENCES; Lugar: New York; Año: 2013 vol. 58 p. 1602 - 1614

CROCENZI, FERNANDO A.; ZUCCHETTI, ANDRÉS ERNESTO; BOAGLIO, ANDREA C; BAROSSO, ISMAEL R.; SÁNCHEZ POZZI, ENRIQUE J; MOTTINO, ALDO D; ROMA, MARCELO G

Localization status of hepatocellular transporters in cholestasis

FRONTIERS IN BIOSCIENCE-LANDMARK; Año: 2012 vol. 17 p. 1201 - 1218

BAROSSO, ISMAEL R.; ZUCCHETTI, ANDRÉS ERNESTO; BOAGLIO, ANDREA C; LAROCCA, M CECILIA; TABORDA, DIEGO; LUQUITA, MARCELO G.; ROMA, MARCELO G; CROCENZI, FERNANDO A.; SÁNCHEZ POZZI, ENRIQUE J

Sequential Activation of Classic PKC and Estrogen Receptor Alfa Is Involved in Estradiol 17ß-D-Glucuronide-Induced Cholestasis

PLOS ONE; Lugar: San Francisco; Año: 2012 vol. 7 p. 1 - 12

BOAGLIO, ANDREA C; ZUCCHETTI, ANDRÉS ERNESTO; TOLEDO, FLAVIA D.; BAROSSO, ISMAEL R.; SÁNCHEZ POZZI, ENRIQUE J; CROCENZI, FERNANDO A.*; ROMA, MARCELO G.*

Erk1/2 and p38 MAPKs are complementarily involved in estradiol 17ß-d-glucuronide-induced cholestasis: crosstalk with cPKC and PI3K.

PLOS ONE; Lugar: San Francisco; Año: 2012 vol. 7 p. 1 - 12

ROMA, MARCELO G; TOLEDO, FLAVIA D.; BOAGLIO, ANDREA C; BASIGLIO, CECILIA L; CROCENZI, FERNANDO A; SÁNCHEZ POZZI, ENRIQUE J

Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications

CLINICAL SCIENCE (LONDON, ENGLAND : 1979); Lugar: Londres; Año: 2011 vol. 121 p. 523 - 544

ZUCCHETTI, ANDRÉS ERNESTO; BAROSSO, ISMAEL R.; BOAGLIO, ANDREA C; PELLEGRINO, JOSÉ M; OCHOA, J. ELENA; ROMA, MARCELO G; CROCENZI, FERNANDO A.; SÁNCHEZ POZZI, ENRIQUE J

Prevention of estradiol 17beta-D-glucuronide-induced canalicular transporter internalization by hormonal modulation of cAMP in rat hepatocytes

MOLECULAR BIOLOGY OF THE CELL; Año: 2011 vol. 22 p. 3902 - 3915

BOAGLIO, ANDREA C; ZUCCHETTI, ANDRÉS ERNESTO; SÁNCHEZ POZZI, ENRIQUE J; PELLEGRINO, JOSÉ M; OCHOA, J. ELENA; MOTTINO, ALDO D; VORE, MARY; CROCENZI, FERNANDO A.; ROMA, MARCELO G

Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17β-D-glucuronide–induced cholestasis: Complementarity with classical protein kinase C

HEPATOLOGY (BALTIMORE, MD.); Lugar: Baltimore, MD; Año: 2010 vol. 52 p. 1465 - 1476

ROMA, MARCELO G.; CROCENZI, FERNANDO A.; MOTTINO, ALDO D.

Dynamic localization of hepatocellular transporters in health and disease.

World J Gastroenterol; Lugar: Beijing; Año: 2008 vol. 14 p. 6786 - 6801

ROMA, MARCELO G.; CROCENZI, FERNANDO ARIEL; SÁNCHEZ POZZI, ENRIQUE J.

Hepatocellular transport in acquired cholestasis: new insights into functional, regulatory and therapeutic aspects

CLINICAL SCIENCE (LONDON, ENGLAND : 1979); Lugar: Londres; Año: 2008 vol. 114 p. 567 - 588

CROCENZI, FERNANDO A.; SÁNCHEZ POZZI, ENRIQUE J; RUIZ, MARÍA LAURA; ZUCCHETTI, ANDRÉS ERNESTO; ROMA, MARCELO G; MOTTINO, ALDO D; VORE, MARY

Ca2+-DEPENDENT PROTEIN KINASE C ISOFORMS ARE CRITICAL TO ESTRADIOL 17ß-D-GLUCURONIDE-INDUCED CHOLESTASIS IN THE RAT

HEPATOLOGY (BALTIMORE, MD.); Año: 2008 vol. 48 p. 1885 - 1895

MOTTINO, ALDO D.; HOFFMAN, TIM; CROCENZI, FERNANDO A.; SÁNCHEZ POZZI, ENRIQUE J.; ROMA, MARCELO G.; VORE, MARY

Disruption of function and localization of tight-junctional structures and Mrp2 in sustained estradiol-17ß-D-glucuronide-induced cholestasis.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Año: 2007 vol. 293 p. 391 - 402

FERNANDO ARIEL CROCENZI; ROMA, MARCELO G.

Silymarin as a New Hepatoprotective Agent in Experimental Cholestasis: New Possibilities for an Ancient Medication

Current Medicinal Chemistry; Año: 2006 vol. 13 p. 1055 - 1074

FERNANDO ARIEL CROCENZI; PELLEGRINO, JOSÉ M.; CATANIA, VIVIANA A.; LUQUITA, MARCELO G.; ROMA, MARCELO G.; MOTTINO, ALDO D.; SÁNCHEZ POZZI, ENRIQUE J.

Galactosamine prevents ethinylestradiol-induced cholestasis

Drug Metabolism and Disposition; Año: 2006 vol. 34 p. 993 - 997

MOTTINO, ALDO D.; FERNANDO ARIEL CROCENZI; SÁNCHEZ POZZI, ENRIQUE J.; VEGGI, LUIS M.; ROMA, MARCELO G.; VORE, MARY

Role of microtubules in estradiol-17ß-D-glucuronide-induced alteration of canalicular mrp2 localization and activity.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Año: 2005 vol. 288 p. 327 - 336

RUIZ, MARÍA LAURA; VILLANUEVA, SILVINA S.M.; LUQUITA, MARCELO G.; SÁNCHEZ POZZI, ENRIQUE J.; FERNANDO ARIEL CROCENZI; PELLEGRINO, JOSÉ M.; OCHOA, J.ELENA; VORE, MARY; MOTTINO, ALDO D.; CATANIA, VIVIANA A.

Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2.

BIOCHEMICAL PHARMACOLOGY; Año: 2005 vol. 69 p. 531 - 539

FERNANDO ARIEL CROCENZI; BASIGLIO, CECILIA L.; PÉREZ, LEONARDO M.; SÁNCHEZ POZZI, ENRIQUE J.; PORTESIO, MARÍA SOLEDAD; ROMA, MARCELO G.

Silibinin prevents cholestasis-associated retrieval of the bile salt export pump, Bsep, in isolated rat hepatocyte couplets: possible involvement of cAMP.

BIOCHEMICAL PHARMACOLOGY; Año: 2005 vol. 69 p. 1113 - 1120

FERNANDO ARIEL CROCENZI; D'ANDREA, VANESA; CATANIA, VIVIANA A.; LUQUITA, MARCELO G.; PELLEGRINO, JOSÉ M.; OCHOA, J.ELENA; MOTTINO, ALDO D.; SÁNCHEZ POZZI, ENRIQUE J.

Prevention of Mrp2 activity impairment in ethinylestradiol-induced cholestasis by ursodeoxycholate in the rat.

Drug Metabolism and Disposition; Año: 2005 vol. 33 p. 888 - 891

VEGGI, LUIS M.; FERNANDO ARIEL CROCENZI; ROMA, MARCELO G.; MOTTINO, ALDO D.

Dapsone impairs the bile-salt independent fraction of bile flow in rats: Possible involvement fo its N-hydroxylated metabolite.

TOXICOLOGY; Año: 2005 vol. 211 p. 97 - 106

FERNANDO ARIEL CROCENZI; MOTTINO, ALDO D.; ROMA, MARCELO G.

Regulation of synthesis and trafficking of canalicular transporters and its alteration in acquired hepatocellular cholestasis: Experimental therapeutic strategies for its prevention.

CURRENT MEDICINAL CHEMISTRY.; Año: 2004 vol. 11 p. 501 - 524

FERNANDO ARIEL CROCENZI; SÁNCHEZ POZZI, ENRIQUE J.; PELLEGRINO, JOSÉ M.; RODRÍGUEZ GARAY, EMILIO A.; MOTTINO, ALDO D.; ROMA, MARCELO G.

Preventive effect of silymarin against taurolithocholate-induced cholestasis in the rat.

BIOCHEMICAL PHARMACOLOGY; Año: 2003 vol. 66 p. 355 - 364

SÁNCHEZ POZZI, ENRIQUE J.; FERNANDO ARIEL CROCENZI; PELLEGRINO, JOSÉ M.; CATANIA, VIVIANA A.; LUQUITA, MARCELO G.; ROMA, MARCELO G.; RODRÍGUEZ GARAY, EMILIO A.; MOTTINO, ALDO D.

Ursodeoxycholate reduces ethinylestradiol glucuronidation in the rat: role in the prevention of estrogen-induced cholestasis.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS; Año: 2003 vol. 306 p. 279 - 286

FERNANDO ARIEL CROCENZI; MOTTINO, ALDO D.; CAO, JINGSONG; VEGGI, LUIS M.; SÁNCHEZ POZZI, ENRIQUE J.; VORE, MARY; COLEMAN, ROGER; ROMA, MARCELO G.

Estradiol-17ß-D-glucuronide induces endocytic internalization of Bsep in rats.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Año: 2003 vol. 285 p. 449 - 459

FERNANDO ARIEL CROCENZI; MOTTINO, ALDO D.; SÁNCHEZ POZZI, ENRIQUE J.; PELLEGRINO, JOSÉ M.; RODRÍGUEZ GARAY, EMILIO A.; MILKIEWICZ, PIOTR; VORE, MARY; COLEMAN, ROGER; ROMA, MARCELO G.

Impaired localisation and transport function of canalicular Bsep in taurolithocholate-induced cholestasis in the rat.

GUT - AN INTERNATIONAL JOURNAL OF GASTROENTEOROLOGY AND HEPATOLOGY; Año: 2003 vol. 52 p. 1170 - 1177

VEGGI, LUIS M.; FERNANDO ARIEL CROCENZI; ROMA, MARCELO G.; DAWSON, PAUL; PELLEGRINO, JOSÉ M.; SÁNCHEZ POZZI, ENRIQUE J.; MOTTINO, ALDO D.

Dapsone-induced cholestasis and impairment of bile salt output in the rat.

BIOCHEMICAL PHARMACOLOGY; Lugar: Oxford, Reino Unido; Año: 2002 vol. 63 p. 1553 - 1563

MOTTINO, ALDO D.; CAO, JINGSONG; VEGGI, LUIS M.; FERNANDO ARIEL CROCENZI; ROMA, MARCELO G.; VORE, MARY

Altered localization and activity of canalicular Mrp2 in estradiol-17b-D-glucuronide-induced cholestasis.

HEPATOLOGY (BALTIMORE, MD.); Año: 2002 vol. 35 p. 1409 - 1419

FERNANDO ARIEL CROCENZI; SÁNCHEZ POZZI, ENRIQUE J.; PELLEGRINO, JOSÉ M.; FAVRE, CRISTIÁN O.; RODRÍGUEZ GARAY, EMILIO A.; MOTTINO, ALDO D.; COLEMAN, ROGER; ROMA, MARCELO G.

Beneficial effects of silymarin on estrogen-induced cholestasis in the rat: A study in vivo and in isolated hepatocyte couplets.

HEPATOLOGY (BALTIMORE, MD.); Año: 2001 vol. 34 p. 329 - 339

FERNANDO ARIEL CROCENZI; PELLEGRINO, JOSÉ M.; SÁNCHEZ POZZI, ENRIQUE J.; MOTTINO, ALDO D.; RODRÍGUEZ GARAY, EMILIO A.; ROMA, MARCELO G.

Effect of silymarin on biliary bile salt secretion in the rat.

BIOCHEMICAL PHARMACOLOGY; Año: 2000 vol. 59 p. 1015 - 1022

FERNANDO ARIEL CROCENZI; SISTI, ALFONSO; PELLEGRINO, JOSÉ M.; ROMA, MARCELO G.

Role of bile salts in colchicine-induced hepatotoxicity. Implications on hepatocellular integrity and function.

TOXICOLOGY; Año: 1997 vol. 121 p. 127 - 142

ROMA, MARCELO G.; FERNANDO ARIEL CROCENZI; RODRÍGUEZ GARAY, EMILIO A.

Does paracellular permeability play a role in cholephilic dye-induced cholestasis?

TOXICOLOGY LETTERS; Año: 1996 vol. 84 p. 13 - 22

ROMA, MARCELO G.; CROCENZI, FERNANDO A; MARINELLI, RAÚL A.; RODRÍGUEZ GARAY, EMILIO A.

Effect of cholephilic dyes on hepatic tight junctional permeability in the rat.

BIOCHEMICAL PHARMACOLOGY; Año: 1995 vol. 50 p. 1079 - 1086