SALAS G.; LITTA A. A.; MEDEOT A. C.; SCHUCK V. S.; ANDERMATTEN R. B.; MISZCZUK G. S.; CIRIACI N.; RAZORI M. V.; BAROSSO I. R.; SÁNCHEZ POZZI E. J.; ROMA M. G.; BASIGLIO, C. L.; CROCENZI F. A.

NADPH oxidase-generated reactive oxygen species are involved in estradiol 17ß-D-glucuronide-induced cholestasis

BIOCHIMIE; Año: 2024

BESSONE F.; HILLOTTE G.L.; AHUMADA N.; JAUREGUIZAHAR F.; MEDEOT A.C.; ROMA M.G.

UDCA for drug-induced liver disease: clinical and pathophysiological basis

SEMINARS IN LIVER DISEASE; Año: 2023

SALAS-SILVA S.; LÓPEZ-RAMIREZ J.; BARRERA-CHIMAL J.; LAZZARINI-LECHUGA R.; SIMONI-NIEVES A.; SOUZA V.; MIRANDA-LABRA R. U.; MASSO F.; ROMA M. G.; GUTIÉRREZ-RUIZ M.C.; BUCIO-ORTIZ L.; GOMEZ-QUIROZ L.E.

Hepatocyte growth factor reverses cholemic nephropathy associated with alpha-naphthylisothiocyanate-induced cholestasis in mice

LIFE SCIENCES; Lugar: Amsterdam; Año: 2022

BASIGLIO C.L.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.; ROMA M.G.

Oxidative stress and localization status of hepatocellular transporters: Impact on bile secretion and role of signaling pathways

ANTIOXIDANTS & REDOX SIGNALING; Año: 2021 vol. 35 p. 808 - 831

BESSONE F.; HERNÁNDEZ N.; TANNO M.; ROMA M.G.

Drug-induced vanishing bile duct syndrome: From pathogenesis to diagnosis and therapeutics

SEMINARS IN LIVER DISEASE; Año: 2021 vol. 41 p. 331 - 348

SALAS-SILVA, S.; SIMONI-NIEVES, A.; RAZORI, M.V.; LÓPEZ-RAMIREZ, J.; BARRERA-CHIMAL, J.; LAZZARINI, R.; BELLO, O.; SOUZA, V.; MIRANDA-LABRA, R.U.; GUTIÉRREZ-RUIZ, M.C.; GOMEZ-QUIROZ, L.E.; ROMA, M.G.*; BUCIO-ORTIZ, L.*

HGF induces protective effects in α-naphthylisothiocyanate-induced intrahepatic cholestasis by counteracting oxidative stress

BIOCHEMICAL PHARMACOLOGY; Año: 2020 vol. 174 p. 113812 - 113812

RAZORI, MARÍA VALERIA; MARTÍN, PAMELA L.; MAIDAGAN, PAULA M.; BAROSSO, ISMAEL R.; CIRIACI, NADIA; ANDERMATTEN, ROMINA B.; SÁNCHEZ POZZI, ENRIQUE J.; BASIGLIO, CECILIA L.; RUIZ, MARÍA LAURA; ROMA, MARCELO G.

Spironolactone ameliorates lipopolysaccharide-induced cholestasis in rats by improving Mrp2 function: Role of transcriptional and post-transcriptional mechanisms

LIFE SCIENCES; Año: 2020 vol. 259 p. 118352 - 118352

MISZCZUK, GISEL S.; BANALES, JESUS M.; ZUCCHETTI, ANDRÉS E.; PISANI, GERARDO B.; BOAGLIO, ANDREA C.; SAEZ, ELENA; MEDINA, JUAN F.; ROMA, MARCELO G.; CROCENZI, FERNANDO A.

Adaptive downregulation of Cl-/HCO3- exchange activity in rat hepatocytes under experimental obstructive cholestasis

PLOS ONE; Lugar: San Francisco; Año: 2019 vol. 14

ROMA M.G.; BAROSSO I.R.; MISZCZUK G.S.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.

Dynamic Localization of Hepatocellular Transporters: Role in Biliary Excretion and Impairment in Cholestasis

CURRENT MEDICINAL CHEMISTRY.; Lugar: Oak Park; Año: 2019 vol. 26 p. 1113 - 1154

SALAS SILVA E.S.; SIMONI-NIEVES A.; LÓPEZ-RAMIREZ J.; BUCIO L.; GÓMEZ-QUIROZ L.E.; GUTIÉRREZ-RUIZ M.C.; ROMA M.G.

Cholangiocyte death in ductopenic cholestatic cholangiopathies: Mechanistic basis and emerging therapeutic strategies

LIFE SCIENCES; Lugar: Amsterdam; Año: 2019 vol. 218 p. 324 - 339

BESSONE F.; RAZORI M.V.; ROMA M.G.

Molecular pathways of nonalcoholic fatty liver disease development and progression

CELL. MOLEC. LIFE SCIEN.; Año: 2019 vol. 76 p. 99 - 128

SALAS SILVA E.S.; SIMONI NIEVES A.; RAZORI M.V.; BARRERA-CHIMAL J.; LÓPEZ RAMÍREZ J.; BUCIO-ORTIZ L.; GÓMEZ QUIROZ L.E.; ROMA, M.G.; GUTIÉRREZ RUIZ M.C.

HGF protector effect in intrahepatic cholestasis

JOURNAL OF HEPATOLOGY; Lugar: Amsterdam; Año: 2019 vol. 70 p. 427 - 428

CIRIACI, NADIA; ANDERMATTEN, ROMINA BELÉN; RAZORI, MARÍA VALERIA; SCHUCK, VIRGINIA SOLEDAD; MISZCZUK, GISEL SABRINA; MEDEOT, ANABELA CAROLINA; CROCENZI, FERNANDO ARIEL; ROMA, MARCELO GABRIEL; BAROSSO, ISMAEL RICARDO; RUIZ, MARÍA LAURA; SÁNCHEZ POZZI, ENRIQUE JUAN

Role of ERK1/2 in TNFα-induced internalization of Abcc2 in rat hepatocyte couplets

BIOCHEMICAL PHARMACOLOGY; Año: 2019 vol. 164 p. 311 - 320

MARTÍN P.L.; CECCATTO P.; RAZORI M.V.; FRANCÉS D.; ARRIAGA S.M.; PISANI G.B.; MARTINEZ A.; SÁNCHEZ POZZI E.J.; ROMA M.G.; BASIGLIO C.L.

Induction of heme oxygenase-1 by hemin prevents oxidative stress-induced acute cholestasis in the rat

CLINICAL SCIENCE (LONDON, ENGLAND : 1979); Lugar: Londres; Año: 2019 vol. 133 p. 117 - 134

RAZORI, MARÍA VALERIA; MAIDAGAN, PAULA M.; CIRIACI, NADIA; ANDERMATTEN, ROMINA B.; BAROSSO, ISMAEL R.; MARTÍN, PAMELA L.; BASIGLIO, CECILIA L.; POZZI, ENRIQUE J. SÁNCHEZ; RUIZ, MARÍA LAURA; ROMA, MARCELO G.

Anticholestatic mechanisms of ursodeoxycholic acid in lipopolysaccharide-induced cholestasis

BIOCHEMICAL PHARMACOLOGY; Año: 2019

ANDERMATTEN, ROMINA BELÉN; CIRIACI, NADIA; SCHUCK, VIRGINIA SOLEDAD; DI SIERVI, NICOLÁS; RAZORI, MARÍA VALERIA; MISZCZUK, GISEL SABRINA; MEDEOT, ANABELA CAROLINA; DAVIO, CARLOS ALBERTO; CROCENZI, FERNANDO ARIEL; ROMA, MARCELO GABRIEL; BAROSSO, ISMAEL RICARDO; SÁNCHEZ POZZI, ENRIQUE JUAN

Sphingosine 1-phosphate receptor 2/adenylyl cyclase/protein kinase A pathway is involved in taurolithocholate-induced internalization of Abcc2 in rats

ARCHIVES OF TOXICOLOGY.; Año: 2019 vol. 93 p. 2279 - 2294

MISZCZUK, GISEL S.; BAROSSO, ISMAEL R.; LAROCCA, MARÍA CECILIA; MARRONE, JULIETA; MARINELLI, RAÚL A.; BOAGLIO, ANDREA C.; SÁNCHEZ POZZI, ENRIQUE J.; ROMA, MARCELO G.; CROCENZI, FERNANDO A.

Mechanisms of canalicular transporter endocytosis in the cholestatic rat liver

BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE; Año: 2018 vol. 1864 p. 1072 - 1085

BESSONE F.; DIRCHWOLF M.; RODIL M.A.; RAZORI M.V.; ROMA M.G.

Review article: drug-induced liver injury in the non-alcoholic fatty liver disease context - A physiopathological and clinical integrated view

ALIMENTARY PHARMACOLOGY & THERAPEUTICS.; Lugar: Londres; Año: 2018 vol. 48 p. 892 - 913

BAROSSO I.R.; MISZCZUK G.S.; CIRIACI N.; ANDERMATTEN R.; MAIDAGAN P.M.; RAZORI M.V.; TABORDA D.R; ROMA M.G.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.

Activation of Insulin-like growth factor 1 receptor participates downstream of GPR30 in estradiol-17ß-D-glucuronide induced cholestasis in rats

ARCHIVES OF TOXICOLOGY.; Año: 2018 vol. 91 p. 2391 - 2406

TOLEDO F.D.; BASIGLIO C.L.; BAROSSO I.R.; BOAGLIO A.C.; ZUCCHETTI A.E.; SÁNCHEZ POZZI E.J.; ROMA M.G.

Mitogen-activated protein kinases are involved in hepatocanalicular dysfunction and cholestasis induced by oxidative stress

ARCHIVES OF TOXICOLOGY.; Lugar: Berlin; Año: 2017 vol. 91 p. 2391 - 2403

BAROSSO I.R.; ZUCCHETTI A.E.; MISZCZUK G.S.; BOAGLIO A.C.; TABORDA D.R.; ROMA M.G.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.

EGFR participates downstream of ERa in estradiol-17ß-D-glucuronide-induced impairment of Abcc2 function in isolated rat hepatocyte couplets

ARCHIVES OF TOXICOLOGY.; Lugar: Berlin; Año: 2016 vol. 90 p. 891 - 903

BESSONE F.; ROMA M.G.

Is ursodeoxycholic acid detrimental in obstructive cholestasis?: apropos a case of malignant biliary obstruction

ANNALS OF HEPATOLOGY; Año: 2016 vol. 15 p. 442 - 447

BESSONE F.; HERNÁNDEZ N.; ROMA M.G.; RIDRUEJO E.; MENDIZÁBAL M.; MEDINA CÁLIZ I.; ROBLES-DÍAS M.; LUCENA M.I.; ANDRADE R.J.

Hepatotoxicity induced by coxibs: How concerned should we be?

EXPERT OPINION ON DRUG SAFETY; Lugar: London; Año: 2016 vol. 15 p. 1463 - 1475

BESSONE F.; LUCENA M.I.; ROMA M.G.; STEPHENS C.; MEDINA-CÁLIZ I.; FRIDER B.; TSARIKTSIAN G.; HERNÁNDEZ N.; BRUGUERA M.; GUALANO G.; FASSIO E.; MONTERO J.; REGGIARDO M.V.; FERRETTI S.; COLOMBATO L.; TANNO F.; FERRER J.; ZENO J.; TANNO H.; ANDRADE R.J.

Cyproterone acetate induces a broad spectrum of acute liver damage including corticosteroid-responsive hepatitis: report of 22 cases

LIVER INTERNATIONAL; Año: 2016 vol. 36 p. 302 - 310

MISZCZUK G.S.; BAROSSO I.R.; ZUCCHETTI A.E.; BOAGLIO A.C.; PELLEGRINO J.M.; SÁNCHEZ POZZI E.J.; ROMA M.G.; CROCENZI F.A.

Sandwich-cultured rat hepatocytes as an in vitro model to study canalicular transport alterations in cholestasis.

ARCHIVES OF TOXICOLOGY.; Lugar: Berlin; Año: 2015 vol. 89 p. 979 - 990

ZUCCHETTI A.E.; BAROSSO I.R.; BOAGLIO A.C.; BASIGLIO C.L.; MISZCZUK G.S.; LAROCCA M.C.; RUIZ M.L.; TABORDA D.R.; LUQUITA M.G.; DAVIO C.; ROMA M.G.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.

G-protein-coupled receptor 30/adenylyl cyclase/protein kinase A pathway is involved in estradiol 17ß-D-glucuronide-induced cholestasis

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2014 vol. 59 p. 1016 - 1029

TOLEDO F.D.; PÉREZ L.M.; BASIGLIO C.L.; OCHOA J.E.; SÁNCHEZ POZZI E.J.; ROMA M.G.

Ca2+-calmodulin-Ca2+/calmodulin-dependent protein kinase II pathway is involved in oxidative stress-induced mitochondrial permeability transition and apoptosis in rat hepatocytes

ARCHIVES OF TOXICOLOGY.; Lugar: Berlin; Año: 2014 vol. 88 p. 1695 - 1709

BESSONE F.; POLES N.; ROMA M.G.

The challenge of liver disease in lupus: clues for diagnosis and hints for pathogenesis.

World Journal of Hepatology; Año: 2014 vol. 6 p. 394 - 409

BASIGLIO C.L.; TOLEDO F.D.; BOAGLIO A.C.; ARRIAGA S.M.; OCHOA J.E.; SÁNCHEZ POZZI E.J.; MOTTINO A.D.; ROMA M.G.

Physiological concentrations of unconjugated bilirubin prevent oxidative stress-induced hepatocanalicular dysfunction and cholestasis

ARCHIVES OF TOXICOLOGY.; Lugar: Berlin; Año: 2014 vol. 88 p. 501 - 514

ROMA M.G.

Ácido ursodesoxicólico en colangiopatías: Cuando, cómo y por qué

Actualizaciones en Hepatología; Lugar: Buenos Aires; Año: 2014 vol. 6 p. 19 - 32

ZUCCHETTI A.E.; BOAGLIO A.C.; BAROSSO I.R.; LUQUITA M.G.; ROMA M.G.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.

Hormonal modulation of hepatic cAMP prevents estradiol 17ß-D-glucuronide-induced cholestasis in perfused rat liver

DIGESTIVE DISEASE AND SCIENCES; Año: 2013 vol. 58 p. 1602 - 1614

BAROSSO I.R.; ZUCCHETTI A.E.; BOAGLIO A.C.; LAROCCA M.C.; TABORDA D.R.; LUQUITA M.G.; ROMA M.G.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.

Sequential activation of classic PKC and estrogen receptor alfa is involved in estradiol 17ß-D-glucuronide-induced cholestasis.

PLOS ONE; Lugar: San Francisco; Año: 2012 vol. 7 p. 1 - 12

CROCENZI F.A.; ZUCCHETTI A.E.; BOAGLIO A.C.; BAROSSO I.R.; SÁNCHEZ POZZI E.J.; MOTTINO A.D.; ROMA M.G.

Localization status of hepatocellular transporters in cholestasis

FRONTIERS IN BIOSCIENCE-LANDMARK; Año: 2012 vol. 17 p. 1201 - 1218

BOAGLIO A.C.; ZUCCHETTI A.E.; TOLEDO F.D.; BAROSSO I.R.; SÁNCHEZ POZZI E.J.; CROCENZI F.A.; ROMA M.G.

Erk1/2 and p38 MAPKs are complementarily involved in estradiol 17ß-D-glucuronide-induced cholestasis: crosstalk with cPKC and PI3K.

PLOS ONE; Lugar: San Francisco; Año: 2012 vol. 7 p. 1 - 12

ZUCCHETTI A.E.; BAROSSO I.R.; BOAGLIO A.C.; PELLEGRINO J.M.; OCHOA, J.E.; ROMA M.G.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.

Prevention of estradiol 17ß-D-glucuronide-induced canalicular transporter internalization by hormonal modulation of cAMP in rat hepatocytes

MOLECULAR BIOLOGY OF THE CELL; Lugar: Bethesda; Año: 2011 vol. 22 p. 3902 - 3915

ROMA M.G.; TOLEDO F.D.; BOAGLIO A.C.; BASIGLIO C.L.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.

Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications

CLINICAL SCIENCE (LONDON, ENGLAND : 1979); Lugar: Londres; Año: 2011 vol. 121 p. 523 - 544

BOAGLIO, A.C.; ZUCCHETTI A.E.; SÁNCHEZ POZZI E.J.; PELLEGRINO J.M.; OCHOA J.E.; MOTTINO A.D.; VORE M.; CROCENZI F.A.; ROMA M.G.

Phosphoinositide 3-kinase/protein kinase B signaling pathway is involved in estradiol 17ß-D-glucuronide-induced cholestasis: Complementarity with classical protein kinase C

HEPATOLOGY; Lugar: Hoboken; Año: 2010 vol. 52 p. 1465 - 1476

BASIGLIO C.L.; MOTTINO A.D.; ROMA M.G.

Tauroursodeoxycholate counteracts hepatocellular lysis induced by tensioactive bile salts by preventing plasma membrane-micelle transition

CHEMICO-BIOLOGICAL INTERACTIONS; Año: 2010 vol. 188 p. 386 - 392

ROMA M.G.

Ácido ursodesoxicólico: Definiendo sus aplicaciones terapéuticas a través de sus mecanismos de acción

Actualizaciones en Hepatología; Lugar: Argentina; Año: 2009 vol. 1 p. 74 - 84

ROMA M.G.; SÁNCHEZ POZZI E.J.

Putative role for actin organization status in the dynamic localization of canalicular carriers under oxidative stress conditions

THE AMERICAN JOURNAL OF PHYSIOLOGY.; Año: 2009 vol. 296 p. 969 - 969

BASIGLIO C.L.; SÁNCHEZ POZZI E.J.; MOTTINO A.D.; ROMA M.G.

Differential effects of silymarin and its active component silibinin on plasma membrane stability and hepatocellular lysis

CHEMICO-BIOLOGICAL INTERACTIONS; Año: 2009 vol. 179 p. 297 - 303

VEGGI L.M.; PRETTO L.; OCHOA E.J.; CATANIA V.A.; LUQUITA M.G.; TABORDA D.R.; SÁNCHEZ POZZI E.J.; IKUSHIRO S.; COLEMAN M.D.; ROMA M.G.; MOTTINO A.D.

Dapsone induces oxidative stress and impairs antioxidant defenses in rat liver

LIFE SCIENCES; Lugar: EE.UU.; Año: 2008 vol. 83 p. 155 - 163

CROCENZI F.A.; SÁNCHEZ POZZI E.J.; RUIZ M.L.; ZUCCHETTI A.E.; ROMA M.G.; MOTTINO A.D.; VORE M.

Ca2+-dependent protein kinase C isoforms are critical to estradiol 17ß-D-glucuronide-induced cholestasis in the rat

HEPATOLOGY; Año: 2008 vol. 48 p. 1885 - 1895

ROMA M.G.; SÁNCHEZ POZZI E.J.

Oxidative stress: A radical way to stop making bile

ANNALS OF HEPATOLOGY; Lugar: Distrito Federal, México; Año: 2008 vol. 7 p. 16 - 33

ROMA M.G.; CROCENZI F.A.; MOTTINO A.D.

Dynamic localization of hepatocellular transporters in health and disease

WORLD JOURNAL OF GASTROENTEROLOGY; Lugar: Beijing; Año: 2008 vol. 14 p. 6786 - 6801

ROMA M.G.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.

Hepatocellular transport in acquired cholestasis: New insights into functional, regulatory and therapeutic aspects.

CLINICAL SCIENCE (LONDON, ENGLAND : 1979); Lugar: Londres; Año: 2008 vol. 114 p. 567 - 588

MOTTINO A.D.; HOFFMAN T.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.; VORE M.; ROMA M.G.

Disruption of function and localization of tight-junctional structures and Mrp2 in sustained estradiol-17-D-glucuronide-induced cholestasis

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Año: 2007 vol. 293 p. 391 - 402

BASIGLIO C.L.; ARRIAGA S.M.; PELUSA, H. F.; ALMARÁ A.; ROMA M.G.; MOTTINO A.D.

Protective role of unconjugated bilirubin on complement-mediated hepatocytolysis

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS; Año: 2007 vol. 1170 p. 1003 - 1010

GONZÁLEZ M. A.; ÁLVAREZ M. L.; PISANI G. B.; BERNAL C. A.; ROMA M. G.; CARRILLO M. C.

Involvement of oxidative stress in the impairment in biliary secretory function induced by intraperitoneal administration of aluminum to rats

BIOLOGICAL TRACE ELEMENT RESEARCH; Año: 2007 vol. 116 p. 329 - 348

PÉREZ L.M.; MILKIEWICZ P.; ELIAS E.; COLEMAN R.; SÁNCHEZ POZZI E.J.; ROMA M.G.

Oxidative stress induces internalization of the bile salt export pump, Bsep, and bile-salt-secretory failure in isolated rat hepatocyte couplets: A role for protein kinase C and prevention by protein kinase A

TOXICOLOGICAL SCIENCES; Año: 2006 vol. 91 p. 150 - 158

PÉREZ L.M.; MILKIEWICZ P.; ELIAS E.; OCHOA, J.E.; SÁNCHEZ POZZI E.J.; ROMA M.G.; COLEMAN R.

Oxidative stress induces actin-cytoskeletal and tight-junctional alterations in hepatocytes by a Ca2+-dependent, PKC-mediated mechanism: Protective effect of PKA.

FREE RADICAL BIOLOGY AND MEDICINE; Año: 2006 vol. 40 p. 2005 - 2017

CROCENZI F.A.; PELLEGRINO J.M.; CATANIA V.A.; LUQUITA M.G.; ROMA M.G.; MOTTINO A.D.; SÁNCHEZ POZZI E.J.

Galactosamine prevents ethinylestradiol-induced cholestasis

Drug Metabolism and Disposition; Año: 2006 vol. 34 p. 993 - 997

CROCENZI F.A.; ROMA M.G.

Silymarin as a new hepatoprotective agent in experimental cholestasis: New possibilities for an ancient medication

CURRENT MEDICINAL CHEMISTRY.; Año: 2006 vol. 13 p. 1055 - 1074

BORGOGNONE M.; PÉREZ L.M.; BASIGLIO C.L.; OCHOA, J.E.; ROMA M.G.

Signaling modulation of bile salt-induced necrosis in isolated rat hepatocytes.

TOXICOLOGICAL SCIENCES; Año: 2005 vol. 83 p. 114 - 125

MOTTINO A.D.; CROCENZI F.A.; SÁNCHEZ POZZI E.J.; VEGGI L.M.; ROMA M.G.; VORE M.

Role of microtubules in estradiol-17ß-D-glucuronide-induced alteration of canalicular mrp2 localization and activity

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Año: 2005 vol. 288 p. 1 - 1

CROCENZI F.A.; BASIGLIO C.L.; PÉREZ L.M.; PORTESIO M.S.; SÁNCHEZ POZZI E.J.; ROMA M.G.

Silibinin prevents cholestasis-associated retrieval of the bile salt export pump, Bsep, in isolated rat hepatocyte couplets: possible involvement of cAMP

BIOCHEMICAL PHARMACOLOGY; Año: 2005 vol. 69 p. 1113 - 1120

VEGGI L.M.; CROCENZI F.A.; ROMA M.G.; MOTTINO A.D.

Dapsone impairs the bile salt-independent fraction of bile flow in rats: possible role for its N-hydroxylated metabolite

TOXICOLOGY; Año: 2005 vol. 211 p. 97 - 106

CROCENZI F.A.; MOTTINO A.D.; ROMA M.G.

Regulation of synthesis and trafficking of canalicular transporters and its alteration in acquired hepatocellular cholestasis: Experimental therapeutic strategies for its prevention (Review article)

CURRENT MEDICINAL CHEMISTRY.; Año: 2004 vol. 11 p. 501 - 524

A GONZÁLEZ, M; ROMA M.G.; ÁLVAREZ M.L.; BERNAL C.A.; CARRILLO, M.C.

Biliary secretory function in rats chronically intoxicated with aluminium

TOXICOLOGICAL SCIENCES; Año: 2004 vol. 79 p. 189 - 195

CROCENZI F.A.; MOTTINO A.D.; SÁNCHEZ POZZI E.J.; PELLEGRINO J.M.; RODRÍGUEZ GARAY E.A.; MILKIEWICZ P.; VORE M.; COLEMAN R.; ROMA M.G.

Impaired localization and transport function of canalicular Bsep in taurolithocholate-induced cholestasis in the rat

GUT - AN INTERNATIONAL JOURNAL OF GASTROENTEOROLOGY AND HEPATOLOGY; Año: 2003 vol. 52 p. 1170 - 1177

CROCENZI F.A.; MOTTINO A.D.; CAO J.; VEGGI L.M.; VORE M.; COLEMAN R.; ROMA M.G.

Estradiol-17ß-D-glucuronide induces endocytic internalization of Bsep in the rat

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Año: 2003 vol. 285 p. 449 - 459

ROMAN I.D.; FERNANDEZ MORENO M.D.; FUEYO J.A.; ROMA M.G.; COLEMAN R.

Cyclosporin A induced internalization of the bile salt export pump in isolated rat hepatocyte couplets

TOXICOLOGICAL SCIENCES; Año: 2003 vol. 71 p. 276 - 281

SÁNCHEZ POZZI E.J.; CROCENZI F.A.; PELLEGRINO J.M.; CATANIA V.A.; LUQUITA M.G.; ROMA M.G.; RODRÍGUEZ GARAY E.A.; MOTTINO A.D.

Ursodeoxycholate reduces ethinylestradiol glucuronidation in the rat: Role in the prevention of estrogen-induced cholestasis

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS; Año: 2003 vol. 306 p. 279 - 286

CROCENZI F.A.; SÁNCHEZ POZZI E.J.; PELLEGRINO J.M.; RODRÍGUEZ GARAY E.A.; MOTTINO A.D.; ROMA M.G.

Preventive effect of silymarin against taurolithocholate-induced cholestasis in the rat

BIOCHEMICAL PHARMACOLOGY; Año: 2003 vol. 66 p. 355 - 364

MOTTINO A.D.; CAO J.; VEGGI L.M.; CROCENZI F.A.; ROMA M.G.; VORE M.

Altered localization and activity of canalicular mrp2 in estradiol-17ß-D-glucuronide-induced cholestasis

HEPATOLOGY; Año: 2002 vol. 35 p. 1409 - 1419

MILKIEWICZ P.; ROMA M.G.; ELIAS E.; COLEMAN R.

Pathobiology and experimental therapeutics in hepatocellular cholestasis: Lessons from the hepatocyte couplet model (Review article)

CLINICAL SCIENCE (LONDON, ENGLAND : 1979); Año: 2002 vol. 102 p. 602 - 613

MILKIEWICZ P.; ROMA M.G.; ELIAS E.; COLEMAN R.

Hepatoprotection with tauroursodeoxycholate and ß-muricholate against taurolithocholate-induced cholestasis: involvement of signal-transduction pathways

GUT - AN INTERNATIONAL JOURNAL OF GASTROENTEOROLOGY AND HEPATOLOGY; Año: 2002 vol. 51 p. 113 - 119

VEGGI L.M.; CROCENZI F.A.; ROMA M.G.; DAWSON P.A.; PELLEGRINO J.M.; SÁNCHEZ POZZI E.J.; MOTTINO A.D.

Dapsone-induced cholestasis and impairment of bile salt output in the rat

BIOCHEMICAL PHARMACOLOGY; Año: 2002 vol. 63 p. 1553 - 1563

CROCENZI F.A.; SÁNCHEZ POZZI E.J.; PELLEGRINO J.M.; FAVRE C.O.; RODRÍGUEZ GARAY E.A.; MOTTINO A.D.; COLEMAN R.; ROMA, MARCELO GABRIEL

Efectos beneficiosos de silimarina en la colestasis por estrógenos en la rata. Estudios in vivo y en duplas aisladas de hepatocitos.

Revista médica de Rosario; Lugar: Rosario; Año: 2002 vol. 68 p. 75 - 84

CROCENZI F.A.; SÁNCHEZ POZZI E.J.; PELLEGRINO J.M.; FAVRE C.O.; RODRÍGUEZ GARAY E.A.; MOTTINO A.D.; COLEMAN R.; ROMA M.G.

Beneficial effects of silymarin on estrogen-induced cholestasis in the rat. A study in vivo and in isolated hepatocyte couplets

HEPATOLOGY (BALTIMORE, MD.); Año: 2001 vol. 34 p. 329 - 339

MILKIEWICZ P.; ROMA M.G.; MILLS C.O.; ELIAS E.; COLEMAN R.

Effect of tauroursodeoxycholate and S-adenosyl-L-methionine on 17ß-estradiol glucuronide-induced cholestasis: A study in rat hepatocyte couplets

JOURNAL OF HEPATOLOGY; Año: 2001 vol. 34 p. 184 - 191

CROCENZI F.A.; PELLEGRINO J.M.; SÁNCHEZ POZZI E.J.; MOTTINO A.D.; RODRÍGUEZ GARAY E.A.; ROMA M.G.

Effect of sylmarin on biliary bile salt secretion in the rat

BIOCHEMICAL PHARMACOLOGY; Año: 2000 vol. 59 p. 1015 - 1022

ROMA M.G.; MILKIEWICZ P.; ELIAS E.; COLEMAN R.

Control by signaling modulators of the sorting of canalicular transporters in rat hepatocyte couplets - Role of the cytoskeleton

HEPATOLOGY (BALTIMORE, MD.); Año: 2000 vol. 32 p. 1342 - 1356

COLEMAN R.; ROMA M.G.

Hepatocyte couplets (Review article)

BIOCHEMICAL SOCIETY TRANSACTIONS; Año: 2000 vol. 28 p. 136 - 140

MILKIEWICZ P.; MILLS C.O.; ROMA M.G.; AHMED CHOUDHURY J.; ELIAS E.; COLEMAN R.

Tauroursodeoxycholate and S-adenosyl-L-methionine exert and additive ameliorating effect of taurolithocholate-induced cholestasis.

HEPATOLOGY; Año: 1999 vol. 29 p. 471 - 476

ROMA M.G.; AHMED CHOUDHURY J.; COLEMAN R.

The protein kinase inhibitor 1-(5-Isoquinolinylsulfonyl)-methyl-piperzine (H-7) prevents and reverses Ca(2+)-mediated injury in isolated rat hepatocyte couplets

TOXICOLOGY AND APPLIED PHARMACOLOGY; Año: 1999 vol. 161 p. 192 - 201

MILLS C.O.; MILKIEWICZ P.; MULLER M.; ROMA M.G.; HAVINGA R.; COLEMAN R.; KUIPERS F.; JANSEN P.L.M.; ELIAS E.

Different pathways of canalicular secretion of fluorescent bile acids: A study in isolated hepatocyte couplets and TR- rats

JOURNAL OF HEPATOLOGY; Año: 1999 vol. 31 p. 678 - 684

ROMA M.G.; STONE V.; SHAW R.; COLEMAN R.

Vasopressin-induced disruption of actin cytoskeletal organization and canalicular function in isolated rat hepatocyte couplets: Possible involvement of protein kinase C

HEPATOLOGY (BALTIMORE, MD.); Año: 1998 vol. 28 p. 1031 - 1041

CROCENZI F.A.; SISTI A.; PELLEGRINO J.M.; ROMA M.G.

Role of bile-salts in colchicine-induced hepatotoxicity: Implications for hepatocellular integrity and function

TOXICOLOGY; Año: 1997 vol. 121 p. 127 - 142

ROMA M.G.; ORSLER D.; COLEMAN R.

Canalicular retention as a marker of tight junctional permeability in isolated hepatocyte couplets: Effects of protein kinase modulation and cholestatic agents.

FUNDAMENTAL AND APPLIED TOXICOLOGY; Año: 1997 vol. 37 p. 71 - 81

CROCENZI F.A.; ROMA M.G.; RODRÍGUEZ GARAY E.A.

Does paracellular permeability play a role in cholephilic dye induced cholestasis?

TOXICOLOGY LETTERS; Año: 1996 vol. 84 p. 13 - 22

SÁNCHEZ POZZI E.J.; MOTTINO A.D.; SISTI A.; ROMA M.G.

Differential effect of ursodeoxycholate and its taurine conjugate on biliary transport maximum of bilirubin in the rat

LIFE SCIENCES; Año: 1995 vol. 57 p. 973 - 981

ROMA M.G.; MARINELLI R.A.; CROCENZI F.A.; RODRÍGUEZ GARAY E.A.

Effect of cholephilic dyes on hepatic tight junctional permeability in the rat

BIOCHEMICAL PHARMACOLOGY; Año: 1995 vol. 50 p. 1079 - 1086

SÁNCHEZ POZZI E.J.; CATANIA V.A.; LUQUITA M.G.; ROMA M.G.; RODRÍGUEZ GARAY E.A.; MOTTINO A.D.

Effect of oral administration of ursodeoxycholic acid on rat hepatic and intestinal UDP-glucuronosyltransferase.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY; Año: 1994 vol. 72 p. 1265 - 1271

ROMA M.G.; PEÑALVA G.L.; AGUERO R.M.; RODRÍGUEZ GARAY E.A.

Hepatic transport of organic anions in taurolithocholate- induced cholestasis in rats

JOURNAL OF HEPATOLOGY; Año: 1994 vol. 20 p. 603 - 610

ROMA M.G.; CARNOVALE C.E.; RODRÍGUEZ GARAY E.A.

Bile salt-associated electrolyte secretion: a study following a short-term biliary obstruction in the rat

EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY; Año: 1992 vol. 44 p. 354 - 360

MARINELLI R.A.; ROMA M.G.; PELLEGRINO J.M.; RODRÍGUEZ GARAY E.A.

Taurolithocholate-induced inhibition of biliary lipid and protein excretion in the rat

BIOCHIMICA AND BIOPHYSICA ACTA; Año: 1992 vol. 1125 p. 44 - 48

ROMA M.G.

Mecanismos fisiopatológicos de colestasis (Actualización)

ACTA GASTROENTEROLOGICA LATINOAMERICANA.; Año: 1992 vol. 22 p. 63 - 78

ROMA M.G.; MARINELLI R.A.; RODRÍGUEZ GARAY E.A.

Biliary excretion of polyethylene glycol M.W. 900: evidence for a bile salt-stimulated vesicular transport mechanism

BIOCHEMICAL PHARMACOLOGY; Año: 1991 vol. 42 p. 1775 - 1781

PELLEGRINO J.M.; ROMA M.G.; MOTTINO A.D.; RODRÍGUEZ GARAY E.A.

Hepatic handling of photoirradiated bilirubin. A study in isolated perfused Wistar rat liver

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS; Año: 1991 vol. 1074 p. 25 - 30

CARNOVALE C.E.; ROMA M.G.; MONTI J.A.; RODRÍGUEZ GARAY E.A.

Studies on the mechanism of bile salt-independent bile flow impairment in streptozotocin-induced hepatotoxicity

TOXICOLOGY; Año: 1991 vol. 68 p. 207 - 215

ROMA M.G.; LUQUE E.A.; MARINELLI R.A.; RODRÍGUEZ GARAY E.A.

A simple method for the correction of biliary excretion curves distorted by the biliary dead space

BIOCHEMICAL PHARMACOLOGY; Año: 1989 vol. 38 p. 4021 - 4025

MOTTINO A.D.; PELLEGRINO J.M.; GUIBERT E.E.; ROMA M.G.; RODRÍGUEZ GARAY E.A.

Comparison of hepatic, renal and intestinal bilirubin-UDP-glucuronyltransferase

INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELLULAR BIOLOGY; Año: 1988 vol. 20 p. 1113 - 1116

ROMA M. G.; LUQUITA M. G.; RODRÍGUEZ GARAY E. A.

Early changes in bile secretion following relief of a short-term biliary obstruction in the rat.

MEDICINA (BUENOS AIRES); Lugar: Buenos Aires; Año: 1988 vol. 48 p. 381 - 388