BIDART, J.; PERTINO, M.W.; SCHMEDA-HIRSCHMANN, G.; ALCHÉ, L.E.; PETRERA, E.

Antiviral Effect of Natural and Semisynthetic Diterpenoids against Adenovirus Infection in vitro

Planta Medica; Año: 2023

BUENO, CARLOS A.; SALINAS, FRANCO M.; VAZQUEZ, L.; ALCHÉ, LAURA E.; MICHELINI, FLAVIA M.

Two synthetic steroid analogs reduce human respiratory syncytial virus replication and the immune response to infection both in vitro and in vivo

Heliyon; Año: 2023 vol. 9

MAIZEL, D.; SALINAS, F.M.; SOLÓRZANO, I.; RAIGER IUSTMAN, L.; FERRERO, M.A.; MAUAS, P.J.D.; ALCHÉ, L.E.

Study of the extremely-tolerant Brevibacterium linens AE038-8 with antiviral activity against Herpes simplex virus type 1

CURRENT MICROBIOLOGY; Lugar: Berlin; Año: 2021

MICHELINI, F.M.; BUENO, C.A.; ARECO, Y.; ALCHÉ, L.E.

A synthetic stigmastane displays antiadenoviral activity and reduces the inflammatory response to viral infection

ANTIVIRAL RESEARCH; Lugar: Amsterdam; Año: 2020

MAIZEL, D.; ALCHÉ L.E.; MAUAS, P.

Poly-extremophiles: exploring the limits of habitability

Memorie della Societa Astronomica Italiana; Año: 2019 vol. 90 p. 658 - 662

SALINAS, FRANCO MAXIMILIANO; VÁZQUEZ, LUCIANA; GENTILINI, MARÍA VIRGINIA; O´DONOHOE, AILIN; REGUEIRA, ELEONORA; NABAES JODAR, MERCEDES SOLEDAD; VIEGAS, MARIANA; MICHELINI, FLAVIA MARIANA; HERMIDA, GLADYS; ALCHÉ, LAURA EDITH; BUENO, CARLOS ALBERTO

Aesculus hippocastanum L. seed extract shows virucidal and antiviral activities against respiratory syncytial virus (RSV) and reduces lung inflammation in vivo

ANTIVIRAL RESEARCH; Año: 2019 vol. 164 p. 1 - 11

PERTINO, M.W.; PETRERA, E.; ALCHÉ, L.E.; SCHMEDA-HIRSCHMANN, G.

Synthesis, Antiviral and Cytotoxic Activity of Novel Terpenyl Hybrid Molecules Prepared by Click Chemistry

MOLECULES; Lugar: Basel; Año: 2018

MICHELINI, F.M.; ALCHÉ, L.E.; BUENO, C.A.

Virucidal, antiviral and immunomodulatory activities of B-escin and Aesculus hippocastanum extract

JOURNAL OF PHARMACY AND PHARMACOLOGY; Año: 2018 vol. 70 p. 1561 - 1571

ZÍGOLO, M. ANTONELA; SALINAS, MAXIMILIANO; ALCHÉ, LAURA; BALDESSARI, ALICIA; LIÑARES, GUADALUPE GARCÍA

Chemoenzymatic synthesis of new derivatives of glycyrrhetinic acid with antiviral activity. Molecular docking study

BIOORGANIC CHEMISTRY; Año: 2018 vol. 78 p. 210 - 219

CHANQUIA, S.N.; BOSCARO,N.V.; ALCHÉ, L.E.; BALDESSARI, A.; GARCÍA LIÑARES, G.

An Efficient Lipase-Catalyzed Synthesis of Fatty AcidDerivatives of Vanillylamine with Antiherpetic Activity inAcyclovir-Resistant Strains

Chemistry Select; Lugar: Weinheim; Año: 2017 vol. 2 p. 1537 - 1546

MICHELINI, F.M.; LOMBARDI, M.G.; BUENO, C.A.; BERRA, A.; SALES, M.E.; ALCHÉ, L.E.

Synthetic stigmasterol derivatives inhibit capillary tube formation, herpetic corneal neovascularization and tumor induced angiogenesis

STEROIDS; Lugar: Amsterdam; Año: 2016 vol. 115 p. 160 - 168

MICHELINI, F.M.; BUENO, C.A.; MOLINARI, A.; GALIGNIANA, M.; GALAGOVSKY, L.R.; ALCHÉ, L.E.; RAMÍREZ, J.A.

Synthetic stigmastanes with dual antiherpetic and immunomodulating activities inhibit ERK and Akt signaling pathways without binding to glucocorticoid receptors

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS; Lugar: Amsterdam; Año: 2016 vol. 1860 p. 129 - 139

RICHMOND VICTORIA; MICHELINI, F.M.; BUENO, C.A.; ALCHÉ, L.E.; RAMÍREZ, J.A.

Small molecules as anti-TNF drugs

CURRENT MEDICINAL CHEMISTRY.; Lugar: Oak Park; Año: 2015 vol. 22 p. 2920 - 2942

ALCHÉ, L.E.

Virest: un remedio para las conjuntivitis virales

QUíMICA VIVA; Lugar: Buenos Aires; Año: 2015

DÁVOLA, M.E.; MAZAIRA, G.I.; GALIGNANA, M.; ALCHÉ, L.E.; RAMÍREZ, J.A.; BARQUERO, A.A.

Synthetic pregnenolone derivatives as antiviral agents against acyclovir-resistant isolates of Herpes Simplex Virus Type 1

ANTIVIRAL RESEARCH; Lugar: Amsterdam; Año: 2015

BUENO, C.A.; MICHELINI, F.M.; PERTINO, M.W.; ARREDONDO GÓMEZ M.C.; SCHMEDA-HIRSCHMANN, G.; ALCHÉ, L.E.

Natural and semisynthetic diterpenoids with antiviral and immunomodulatory activities block the ERK signaling pathway

MEDICAL MICROBIOLOGY AND IMMUNOLOGY; Lugar: Berlin; Año: 2015 vol. 204 p. 575 - 584

CAREAGA, V.; BUENO, C.A.; MUNIAIN, C.; ALCHÉ, L.E.; MAIER, M.S.

Pseudocnoside A, a new cytotoxic and antiproliferative triterpene glycoside from the sea cucumber Pseudocnus dubiosus leoninus

NATURAL PRODUCT RESEARCH; Lugar: Londres; Año: 2014 vol. 28 p. 213 - 220

BARQUERO, A.A.; DÁVOLA, M.E.; RIVA, D.A.; MERSICH, S.E.; ALCHÉ, L.E.

Naturally occurring compounds elicit HIV-1 replication in chronically infected promonocytic cells

BIOMED RESEARCH INTERNATIONAL; Lugar: Akron, Ohio; Año: 2014 vol. 2014 p. 1 - 6

PETRERA, E.; NÍTTOLO, A.G.; ALCHÉ, L.E.

Antiviral action of synthetic stigmasterol derivatives on Herpes Simplex Virus replication in nervous cells in vitro

BIOMED RESEARCH INTERNATIONAL; Lugar: Akron, Ohio; Año: 2014

MICHELINI, F.M.; ZORRILLA P.; ROBELLO, C.; ALCHÉ, L.E.

Immunomodulatory activity of an anti-HSV-1 synthetic stigmastane analog

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: Amsterdam; Año: 2013 vol. 21 p. 560 - 568

BUENO, C.A.; LOMBARDI, M.G.; SALES, M.E.; ALCHÉ, L.E.

A NATURAL ANTIVIRAL AND IMMUNOMODULATORY COMPOUND WITH ANTIANGIOGENIC PROPERTIES

MICROVASCULAR RESEARCH; Lugar: Amsterdam; Año: 2012 vol. 84 p. 235 - 241

BUENO, C.A.; ALCHÉ, LAURA E.; BARQUERO, A.A.

1-Cinnamoyl-3,11-dihydroxymeliacarpin delays glycoprotein transport

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2010 vol. 393 p. 32 - 37

NTALLI, N.; COTTIGLIA, F.; BUENO, C.A.; ALCHE, L.E.; LEONTI, M.; VARGIN, S.; BIFULCO, E.; SPIROUDI, U.; CABONI, P.

Cytotoxic tirucullane triterpenoids from Melia azedarach fruits

MOLECULES; Año: 2010 vol. 15 p. 5866 - 5877

BUENO C.A.; BARQUERO A.A.; DI CÓNSOLI H.; MAIER M.S.; ALCHÉ L.E.

A natural tetranortriterpenoid with immunomodulating properties as a potential anti-HSV agent

VIRUS RESEARCH; Año: 2009 vol. 141 p. 47 - 54

CAREAGA, V.; BUENO C.; MUNIAIN, C.; ALCHÉ, L.; MAIER M.S.

Antiproliferative, cytotoxic and hemolytic activities of a triterpene glycoside from Psolus patagonicus and its desulfated analog

CHEMOTHERAPY; Año: 2009 vol. 55 p. 60 - 68

MICHELINI, F.M.; RAMÍREZ, J.; BERRA, A.; GALAGOVSKY, L.R.; ALCHÉ, L.E.

Anti-herpetic and anti-inflammatory activities of two new synthetic 22,23-dihydroxylated stigmastane derivatives

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY; Año: 2008 vol. 111 p. 111 - 116

MICHELINI, F.M.; BERRA, A.; ALCHÉ, L.E.

The in vitro immunomodulatory activity of a synthetic brassinosteroid analogue would account for the improvement of herpetic stromal keratitis in mice

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY; Año: 2008 vol. 108 p. 164 - 170

RAMÍREZ, J.; BRUTTOMESSO, A.; MICHELINI, F.M.; ACEBEDO, S.; ALCHÉ, L.E.; GALAGOVSKY, L.R.

Syntheses of immunomodulating androstanes and stigmastanes. Comparison of their TNF-á inhibitory activity

BIOORGANIC & MEDICINAL CHEMISTRY.; Año: 2007 vol. 15 p. 7538 - 7544

BARQUERO A.A.; MICHELINI F.M; ALCHÉ L.E.

1-cinnamoyl-3,11-dihydroxymeliacarpin is a natural bioactive compound with antiviral and nuclear factor kB modulating properties

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2006 vol. 344 p. 955 - 962

BARQUERO, A.A.; ALCHÉ, L.E.; COTO, C.E.

Block of VSV endocytic and exocytic pathways by 1- cinnamoyl-3,11- dihydroxymeliacarpin, a tetranortriterpenoid of natural origin

JOURNAL OF GENERAL VIROLOGY; Lugar: Londres; Año: 2004 vol. 85 p. 483 - 493

MICHELINI, F.M.; RAMÍREZ, J.; BERRA, A.; GALAGOVSKY, L.R.; ALCHÉ, L.E.

In vitro and in vivo antiherpetic activity of three new synthetic brassinosteroid analogues

STEROIDS; Año: 2004 vol. 69 p. 713 - 720

ADROVER, M.; GUYOT-REVOL, V.; CHELI, V.T.; BLANCO, E.; VIDAL, R.; ALCHÉ, L.E.; KORNISIUK, E.; EPSTEIN, A.L.; JERUSALINSKY, D.

Hippocampal infection with HSV-1-derived vectors expressing an NMDAR1 antisense modifies behavior

Genes, Brain and Behavior; Año: 2003 vol. 2 p. 1 - 11

ALCHÉ, L.E.; ASSAD FEREK, G.; MEO, M.; COTO, C.E.; MAIER, M.S.

An antiviral meliacarpin from leaves of Melia azedarach L.

ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES; Año: 2003 vol. 58c p. 215 - 219

CHELI, V.T. ; ADROVER, M.; BLANCO, E.; RIAL VERDE, E.; GUYOT-REVOL, V.; VIDAL, R.; MARTÍN, E.; ALCHÉ, L.E.; SANCHEZ, G.; ACERBO, M.; EPSTEIN, A.L.; JERUSALINSKY, D.

Gene transfer of NMDAR1 subunit sequences to the rat CNS using Herpes Simplex Virus vectors interfered with habituation

CELLULAR AND MOLECULAR NEUROBIOLOGY.; Lugar: New York; Año: 2002 vol. 22 p. 303 - 314

ALCHÉ, L.E.; BARQUERO, A.A.; SANJUAN, N.A.; COTO, C.E.

An antiviral principle present in a purified fraction from Melia azedarach L. leaf aqueous extract restrains Herpes simplex virus type 1 propagation

PHYTOTHERAPY RESEARCH; Año: 2002 vol. 16 p. 348 - 352

PIFARRÉ, M.P.; BERRA, A.; COTO, C.E.; ALCHÉ, L.E.

Therapeutic action of meliacine, a plant-derived antiviral, on HSV-induced ocular disease in mice

EXPERIMENTAL EYE RESEARCH; Lugar: Manchester; Año: 2002 vol. 75 p. 327 - 334

ALCHÉ, L.E.; BERRA, A.; COTO, C.E.

Effective treatment of mouse herpetic stromal keratitis with meliacine, a plant-derived antiviral

International Antiviral News; Lugar: London; Año: 2001 vol. 9 p. 132 - 135

ALCHÉ, L.E.; BERRA, A.; VELOSO, M.J.; COTO, C.E.

Treatment with meliacine, a plant derived antiviral, prevents the development of herpetic stromal keratitis in mice

JOURNAL OF MEDICAL VIROLOGY; Año: 2000 vol. 61 p. 474 - 480

BARQUERO, A.A.; ALCHÉ, L.E.; COTO, C.E.

Antiviral activity of meliacine on the replication of a thymidine kinase deficient mutant of Herpes simplex virus type I alone and in combination with acyclovir

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS; Lugar: Amsterdam; Año: 1997 vol. 9 p. 49 - 55

VILLAMIL, S.; ALCHÉ, L.E.; COTO, C.E.

Inhibition of herpes sinplex virus type l multiplication by meliacine, a peptide of plant origin

ANTIVIRAL CHEMISTRY & CHEMOTHERAPY; Año: 1995 vol. 6 p. 239 - 244

ALCHÉ, L.E.; COTO, C.E.

In vitro selection of Junín virus antigenic variants

ARCHIVES OF VIROLOGY; Lugar: Viena; Año: 1993 vol. 128 p. 389 - 394

ALCHÉ, L.E.; COTO, C.E.

Differentiation of Junín virus and antigenic variants isolated in vivo by kinetic neutralization assays

JOURNAL OF GENERAL VIROLOGY; Año: 1988 vol. 69 p. 2123 - 2127

ALCHÉ, L.E.; COULOMBIÉ, F.C.; COTO, C.E.

Isolation of Junin virus from blood and peripheral lymphocytes of infected Calomys musculinus

Revista Argentina de Microbiología; Año: 1986 vol. 17 p. 177 - 181

COULOMBIÉ, F.C.; ALCHÉ, L.E.; LAMPURI, J.S.; COTO, C.E.

Role of Calomys musculinus peritoneal macrophages in age related resistance to Junín virus infection

JOURNAL OF MEDICAL VIROLOGY; Año: 1986 vol. 18 p. 289 - 298

ALCHÉ, L.E.; COTO, C.E.

Antigenic variants of Junín virus isolated from infected Calomys musculinus

ARCHIVES OF VIROLOGY; Lugar: Viena; Año: 1986 vol. 90 p. 343 - 348