Efectos de diferentes fuentes de ácidos grasos n-3 (chía, vegetal y marina, animal) sobre componentes del síndrome metabólico en modelos experimentales (ratas/ratones)

DAIANA GISEL MARANO; PAMELA ROCÍO FERNÁNDEZ; MARÍA EUGENIA D'ALESSANDRO

Actualización en Nutrición

Biotecnológica

Lugar: Buenos Aires; Año: 2021 vol. 20 p. 94 - 104

1667-8052

Introduction: the metabolic syndrome (MS) constitutes a constellation of interrelated factors that increase the risk of suffering cardiovascular disease and diabetes mellitus type 2. The composition of the diet is crucial in the modification of these factors. Numerous works focused attention on sources of n-3 fatty acids of marine (animal) origin in the management of these disorders, but scarce and more contemporary are those of n-3 of plant sources. Objectives: to carry out a critical analysis of the experimental scientific evidence of the effects of a vegetable source (Salvia hispanica L. -chia-) and another animal (marine) of n-3 fatty acids on metabolic alterations present in the SM. Materials and methods: descriptive and observational study applied to a sample of 32 scientific articles. The effects of n-3 fatty acids (seed/oil chia and marine oils) on different SMrelated parameters were analyzed in experimental models induced by diets rich in simple sugars and/or fats. Results: both sources of n-3 improve triglycerides, total cholesterol and plasma free fatty acids levels, glycemia, insulin sensitivity, glucose tolerance, weight of adipose tissue (visceral), systolic blood pressure, size of adipocytes, hepatic triglycerides, proinflammatory markers and lipogenic and antioxidants enzymes activities. Conclusions: the vegetable and marine source of n-3showed beneficial effects on some risk factors of MS, becoming to the seed/oil of chia as a novel alternative to the traditional marine source in the management of these disorders.