Subcellular localization and post-secretory targeting of TgPI, a serine proteinase inhibitor from Toxoplasma gondii.

PSZENNY, V; LEDESMA, B.; MATRAJT, M; DUSCHAK, V.; BONTEMPI, E.; DUBREMETZ, J.; SERGIO OSCAR ANGEL

MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Año: 2002 vol. 121 p. 283 - 286

0166-6851

we have shown that the T. gondii widerange serpin TgPI is a dense granule protein that is released in the lumen of PV by the tachyzoite after host cell entry, and that is also expressed during bradyzoite stage. Its physiological role remains an intriguing and interesting opened question.