Global characteristics and outcomes of SARS-CoV-2 infection in children and adolescents with cancer (GRCCC): a cohort study

MUKKADA, SHEENA; BHAKTA, NICKHILL; CHANTADA, GUILLERMO L; CHEN, YICHEN; VEDARAJU, YUVANESH; FAUGHNAN, LANE; HOMSI, MAYSAM R; MUNIZ-TALAVERA, HILMARIE; RANADIVE, RADHIKESH; METZGER, MONIKA; FRIEDRICH, PAOLA; AGULNIK, ASYA; JEHA, SIMA; LAM, CATHERINE; DALVI, RASHMI; HESSISSEN, LAILA; MOREIRA, DANIEL C; SANTANA, VICTOR M; SULLIVAN, MICHAEL; BOUFFET, ERIC; CANIZA, MIGUELA A; DEVIDAS, MEENAKSHI; PRITCHARD-JONES, KATHY; RODRIGUEZ-GALINDO, CARLOS; RIBELLES, A JUAN; BALDUZZI, ADRIANA; ELHADDAD, ALAA; CASANOVAS, ALEJANDRA; GARCIA VELAZQUEZ, ALEJANDRA; LAPTSEVICH, ALIAKSANDRA; CHANG, ALICIA; F. SAMPAIO, ALESSANDRA LAMENHA; GONZÁLEZ PRIETO, ALMUDENA; LASSALETTA, ALVARO; SUAREZ M, AMARANTO; ALCASABAS, ANA PATRICIA; COLITA, ANCA; MORALES LA MADRID, ANDRES; SAMUDIO, ANGÉLICA; TONDO, ANNALISA; COLOMBINI, ANTONELLA; KATTAMIS, ANTONIS; LOPEZ FACUNDO, N ARACELI; BHATTACHARYYA, ARPITA; ALIMI, AURÉLIA; PHULPIN, AURÉLIE; VAKRMANOVA, BARBORA; AKSOY, BASAK A; BRETHON, BENOIT; KOBUIN, JATOR BRIAN; NOLASCO MONTEIRO, CARLA; PAILLARD,

LANCET ONCOLOGY

ELSEVIER SCIENCE INC

Año: 2021 vol. 22 p. 1416 - 1426

1470-2045

Background: Previous studies have shown that children and adolescents with COVID-19 generally have mild disease. Children and adolescents with cancer, however, can have severe disease when infected with respiratory viruses. In this study, we aimed to understand the clinical course and outcomes of SARS-CoV-2 infection in children and adolescents with cancer. Methods: We did a cohort study with data from 131 institutions in 45 countries. We created the Global Registry of COVID-19 in Childhood Cancer to capture de-identified data pertaining to laboratory-confirmed SARS-CoV-2 infections in children and adolescents (