INFIQC   05475
INSTITUTO DE INVESTIGACIONES EN FISICO- QUIMICA DE CORDOBA
Unidad Ejecutora - UE
artículos
Título:
DOBLE ROLE OF BATHOCUPROINE DISULFONIC ACID AS MULTIWALLED CARBON NANOTUBES DISPERSING AGENT AND COPPER PRECONCENTRATION LIGAND: ANALYTICAL APPLICATIONS FOR THE DEVELOPMENT OF HYDROGEN PEROXIDE AND GLUCOSE ELECTROCHEMICAL SENSORS
Autor/es:
GALLAY, PABLO; GUSTAVO A. RIVAS; MARCOS EGUILAZ RUBIO; MARCELA C. RODRIGUEZ
Revista:
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2020 vol. 191 p. 113526 - 113526
ISSN:
0731-7085
Resumen:
We are reporting a new strategy for preparing carbon nanotubes (CNTs)-basedhydrogen peroxide and glucose amperometric sensors by taking advantage ofthe dual role of bathocuproine disulfonic acid (BCS) as dispersing agent of multiwalledcarbon nanotubes (MWCNTs) and as ligand for the preconcentration ofCu(II). The platform was obtained by casting glassy carbon electrodes (GCE) withthe dispersion of MWCNTs in BCS (MWCNTs-BCS) followed by thepreconcentration of Cu(II) by surface complex formation at open circuit potential(GCE/MWCNTs-BCS/Cu). The resulting electrode was used for the sensitiveamperometric quantification of hydrogen peroxide at 0.400 V catalyzed by thepreconcentrated copper, with a linear range between 5.0 x 10-7 and 7.4 x 10-6 M,a sensitivity of 24.3 mA.M-1, and a detection limit of 0.2 uM. The adsorption of GOx at GCE/MWCNTs-BCS/Cu followed by theimmobilization of Nafion (Naf), allowed the construction of a sensitive andselective amperometric glucose biosensor with a linear range between 5.0 x 10-6 M and 4.9 x 10-4 M, a sensitivity of (477 ± 3) uA.M-1 and a detection limit of 2M. The proposed (bio)sensors were successfully used for the quantification ofhydrogen peroxide in enriched milk samples and glucose in milk and commercialbeverages without any pretreatment.