Solid-gas reactions for nitroxyl (HNO) generation in the gas phase

CARRONE, GUILLERMO; MAZZEO, AGOSTINA; MARCECA, ERNESTO; PELLEGRINO, JUAN; SUÁREZ, SEBASTIÁN; ZARENKIEWICZ, JESSICA; TOSCANO, JOHN P.; DOCTOROVICH, FABIO

JOURNAL OF INORGANIC BIOCHEMISTRY

ELSEVIER SCIENCE INC

Año: 2021

0162-0134

A novel nitroxyl (HNO) generation method is presented, which consists of the reaction between a gaseous base and an HNO donor in the solid phase, allowing the formation of gaseous HNO in a fast and economical way. This method avoids the need of using a liquid system or extreme experimental conditions, and allows to obtain HNO directly in the gas phase for medical use or other applications