Discovery of a b-glucosidase inhibitor from a Chemically Engineered Extract prepared through sulfonylation

SALAZAR, MARIO O.; MICHELONI, OSCAR; ESCALANTE, ANDREA M.; FURLáN, RICARDO L. E.

MOLECULAR DIVERSITY

SPRINGER

Año: 2011 vol. 15 p. 713 - 719

1381-1991

A semisynthetic â-glucosidase inhibitor was identified from a chemically engineered extract prepared by reaction with benzenesulfonyl chloride. The structure includes a natural histamine portion and a benzenesulfonyl portion introduced during the diversification step. identified from a chemically engineered extract prepared by reaction with benzenesulfonyl chloride. The structure includes a natural histamine portion and a benzenesulfonyl portion introduced during the diversification step. identified from a chemically engineered extract prepared by reaction with benzenesulfonyl chloride. The structure includes a natural histamine portion and a benzenesulfonyl portion introduced during the diversification step. â-glucosidase inhibitor was identified from a chemically engineered extract prepared by reaction with benzenesulfonyl chloride. The structure includes a natural histamine portion and a benzenesulfonyl portion introduced during the diversification step.