The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science

IBANEZ, AGUSTIN; YOKOYAMA, JENNIFER S.; POSSIN, KATHERINE L.; MATALLANA, DIANA; LOPERA, FRANCISCO; NITRINI, RICARDO; TAKADA, LEONEL T.; CUSTODIO, NILTON; SOSA ORTIZ, ANA LUISA; AVILA-FUNES, JOSÉ ALBERTO; BEHRENS, MARIA ISABEL; SLACHEVSKY, ANDREA; MYERS, RICHARD M.; COCHRAN, J. NICHOLAS; BRUSCO, LUIS IGNACIO; BRUNO, MARTIN A.; BRUCKI, SONIA M. D.; PINA-ESCUDERO, STEFANIE DANIELLE; OKADA DE OLIVEIRA, MAIRA; DONNELLY KEHOE, PATRICIO; GARCIA, ADOLFO M.; CARDONA, JUAN FELIPE; SANTAMARIA-GARCIA, HERNANDO; MOGUILNER, SEBASTIAN; DURAN-ANIOTZ, CLAUDIA; TAGLIAZUCCHI, ENZO; MAITO, MARCELO; LONGORIA IBARROLA, ERIKA MARIANA; PINTADO-CAIPA, MARITZA; GODOY, MARIA EUGENIA; BAKMAN, VERA; JAVANDEL, SHIREEN; KOSIK, KENNETH S.; VALCOUR, VICTOR; MILLER, BRUCE L.

Frontiers in Neurology

Frontiers Media

Año: 2021 vol. 12

Dementia is becoming increasingly prevalent in Latin America, contrasting with stableor declining rates in North America and Europe. This scenario places unprecedentedclinical, social, and economic burden upon patients, families, and health systems. Thechallenges prove particularly pressing for conditions with highly specific diagnosticand management demands, such as frontotemporal dementia. Here we introducea research and networking initiative designed to tackle these ensuing hurdles, theMulti-partner consortium to expand dementia research in Latin America (ReDLat). First,we present ReDLat?s regional research framework, aimed at identifying the uniquegenetic, social, and economic factors driving the presentation of frontotemporal dementiaand Alzheimer?s disease in Latin America relative to the US. We describe ongoingReDLat studies in various fields and ongoing research extensions. Then, we introduceactions coordinated by ReDLat and the Latin America and Caribbean Consortiumon Dementia (LAC-CD) to develop culturally appropriate diagnostic tools, regionalvisibility and capacity building, diplomatic coordination in local priority areas, and aknowledge-to-action framework toward a regional action plan. Together, these researchand networking initiatives will help to establish strong cross-national bonds, support theimplementation of regional dementia plans, enhance health systems? infrastructure, andincrease translational research collaborations across the continent