World disparities in risk definition and management of retinoblastoma: a report from the International Retinoblastoma Staging Working Group.

CHANTADA GL1, DOZ F, ORJUELA M, QADDOUMI I, SITORUS RS, KEPAK T, FURMANCHUK A, CASTELLANOS M, SHARMA T, CHEVEZ-BARRIOS P, RODRIGUEZ-GALINDO C; INTERNATIONAL RETINOBLASTOMA STAGING WORKING GROUP.

Pediatr Blood Cancer

Wiley

Año: 2008 p. 692 - 694

Following from the publication of the International Retinoblastoma Staging System, an open internet discussion group was created at the www.cure4kids.org resource. The results of a survey distributed among participants are discussed. Although most patients with retinoblastoma were treated under prospective protocols, there was a wide variation in the definition of risk criteria and in the criteria for giving adjuvant chemotherapy following enucleation. Definition of high-risk histological features and the criteria for use of adjuvant therapy will be standardized in future studies. Internet meetings are a valuable mechanism for enabling participation from under-resourced countries in the development of cooperative studies.