Irradiation of Polystyrene and Polypropylene to study NIH 3T3 fibroblasts adhesion

C. R. ARBEITMAN; M. F. DEL GROSSO; I. IBAÑEZ; G. GARCÍA BERMÚDEZ; H. DURÁN; V. C. CHAPPA; R. O. MAZZEI; M. BEHAR

NUCLEAR INSTRUMENTS AND METHODS IN PHYSICS RESEARCH B - BEAM INTERACTIONS WITH MATERIALS AND ATOMS

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2010 vol. 268 p. 3059 - 3062

0168-583X

When polymers are irradiated with heavy ions new chemical groups are created ina few microns of the material. The irradiation changed the polarity and wettabilityon the surface so that could enhance the biocompatibility of the modified polymer.The study of chemistry and nanoscale topography of the biomaterial is important indetermining its potential applications in medicine and biotechnology, because theirstrong influence on cell function, adhesion and proliferation. In this study, thin filmsof Polystyrene and Polypropylene samples were modified by irradiation with lowenergy ion beams (30-150 keV) and swift heavy ions both with various fluences andenergies. The changes were evaluated with different methods. Adhesion of NIH 3T3fibroblasts onto unirradiated and irradiated surfaces has been studied by in vitrotechniques. The correlations between physicochemical properties as a function ofdifferent irradiations parameters were compared with cell adhesion on the modifiedpolymer surface.