Wild pigs (Sus scrofa) population as reservoirs for deleterious mutations in the RYR1 gene associated with Porcine Stress Syndrome

ACOSTA, DIANA BELÉN; ESPAÑOL, LAUREANO ÁNGEL; FIGUEROA, CARLOS EZEQUIEL; MARINI, SEBASTIÁN JOSÉ; MAC ALLISTER, MATÍAS EXEQUIEL; CARPINETTI, BRUNO NICOLÁS; FERNÁNDEZ, GABRIELA PAULA; MERINO, MARIANO LISANDRO

Veterinary and Animal Science

Elsevier

Año: 2021 vol. 11

2451-943X

Porcine Stress Syndrome (PSS) is a disorder codified by the ryanodine receptor 1 gene (RYR1) and affects bothanimal welfare and the quality of the meat product. As a consequence, individuals with this syndrome generategreat worldwide economic losses in the porcine industry. In Argentina, the Buenos Aires Province is the mostinvolved on this activity, and productions are to be in open field with a higher frequency of pigs with diversepathologies. On the other hand, the biggest and oldest wild pigs population is located on the Atlantic coast ofBuenos Aires Province, which presents a continuous bidirectional flow of individuals with the productive areasnearby. The aim of this study is to detect the presence of the RYR1 deleterious allele in the wild population fromthe Atlantic coast of Buenos Aires, in order to evaluate its possible role as a genetic reservoir for said allele. Forthis purpose, 106 wild pigs from 28 sites were studied, finding a 6.6% of carrier individuals, indicating that thewild population is not free of this allele. This constitutes the first analysis to detect the presence of the RYR1deleterious allele, associated to the PSS in wild pigs from Argentina, being one of the few studies to report itworldwide and suggesting wild pigs populations to be a possible genetic reservoir for this disease.