CIFASIS 20631
CENTRO INTERNACIONAL FRANCO ARGENTINO DE CIENCIAS DE LA INFORMACION Y DE SISTEMAS
Unidad Ejecutora - UE
artículos
Título:
A Preliminary Comparison of P-Tool Consistency
Autor/es:
TAPIA, ELIZABETH; GUILLAUME, SERGE; DESTERCKE, SEBASTIEN; SPETALE, FLAVIO; CAILLOUX, OLIVIER; FERNANDEZ, TAMARA; BULACIO, PILAR; MURILLO, JAVIER; KRSTICEVIC, FLAVIA; VAZQUEZ, GUSTAVO; PONCE, SERGIO
Revista:
IFMBE PROCEEDINGS
Editorial:
Springer, Cham
Referencias:
Lugar: Cham; Año: 2020 vol. 75 p. 731 - 735
ISSN:
1680-0737
Resumen:
Many Bioinformatics tools, known as p-tools, have been developed to predict the effect of single nucleotide polymorphisms (SNPs) on gene functionality, in an effort to reduce the need for in-vivo assays. However, the large number of p-tools available and the hetero-geneity of their output make their selection and comparison difficult.To study the consistency of predictions across p-tools, here we present two indices and test them on five p-tools whose predictions are based on different types of background information. For this test, SNPs from well-known organism Drosophila melanogaster are considered.
