Liver transplantation in adults with acute liver failure: Outcomes from the Argentinean Transplant Registry

MENDIZABAL, MANUEL; TAGLIAFICHI, VIVIANA; RUBINSTEIN, FERNANDO; ROJAS, PALOMA; MARCIANO, SEBASTÍAN; YANTORNO, SILVINA; CEJAS, NORA; BARRABINO, MARTÍN; ANDERS, MARGARITA; CAIRO, FERNANDO; VILLAMIL, FEDERICO; BLAZQUEZ, LAURA; ZEREGA, ALINA; FERRETTI, SEBASTIÁN; FERNÁNDEZ, DIEGO; PAREDES, SEBASTIÁN; ABALLAY SOTERAS, GABRIEL; GAITE, LUIS; BISIGNIANO, LILIANA; SILVA, MARCELO O.

ANNALS OF HEPATOLOGY

MEXICAN ASSOC HEPATOLOGY

Año: 2019 vol. 18 p. 338 - 344

1665-2681

Introduction and aim: Liver transplantation (LT) for acute liver failure (ALF) still has a high early mortality. We aimed to evaluate changes occurring in recent years and identify risk factors for poor outcomes.Material and methods: Data were retrospectively obtained from the Argentinean Transplant Registry from two time periods (1998-2005 and 2006-2016). We used survival analysis to evaluate risk of death.Results: A total of 561 patients were listed for LT (69% female, mean age 39.5±16.4 years). Between early and later periods there was a reduction in wait-list mortality from 27% to 19% (p