INVESTIGADORES
DURAN Fernando Javier
artículos
Título:
Enantioselective Intramolecular Copper-Catalyzed Aziridination of Sulfamates
Autor/es:
A. ESTÉOULE; F. J. DURÁN; P. RETAILLEAU; R. H. DODD; P. DAUBAN
Revista:
SYNTHESIS-STUTTGART
Editorial:
Georg Thieme Verlag Stuttgart
Referencias:
Lugar: Stuttgart; Año: 2007 vol. 2007 p. 1251 - 1260
ISSN:
0039-7881
Resumen:
Intramolecular copper-catalyzed aziridination of sulfamates occurs in very good yields of up to 86% and in up to 84% ee in the presence of (4S,4´S)-2,2¢-(propane-2,2-diyl)bis(4-tert-butyl-4,5-dihydro-1,3-oxazole). The resulting aziridines undergo smooth ring opening with different types of nucleophiles in an SN2-type process.
