INVESTIGADORES
MUNICOY Sofia
artículos
Título:
A CATALASE-MAGNETIC SWITCH FOR CELL PROLIFERATION
Autor/es:
MUNICOY SOFIA; IBAÑEZ IRENE L.; DURAN HEBE ; BELLINO MARTIN G.
Revista:
RSC ADVANCES
Editorial:
ROYAL SOCIETY OF CHEMISTRY
Referencias:
Año: 2014 vol. 4 p. 15077 - 15080
ISSN:
2046-2069
Resumen:
The advance of novel biotechnology requires the development of versatile control systems for cell behavior. Towards the vision of cell growth control, we report a magnetic switching in cell proliferation by a catalase-nanomagnetite complex. The system synergically exploits both the ability of catalase to scavenge cell-generated hydrogen peroxide, a messenger involved in cell cycle regulation, and magnetite manipulation to modulate cell proliferation between arrest and growth using magnetic fields. This ON/OFF switch methodology therapeutic strategies as well as novel integrated responsivebiomaterials.
