INVESTIGADORES
DELPINO Maria Victoria
artículos
Título:
Occupational infection due to Brucella abortus S19 among workers involved in vaccine production in Argentine.
Autor/es:
JORGE WALLACH; MARIANA FERRERO; M VICTORIA DELPINO; C. ALBERTO FOSSATI; PABLO C BALDI
Revista:
CLINICAL MICROBIOLOGY AND INFECTION
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Año: 2008 vol. 14 p. 805 - 807
ISSN:
1198-743X
Resumen:
The pathological consequences of exposure to the
vaccine strain Brucella abortus S19 were evaluated
in 30 employees from vaccine-manufacturing
plants. Active brucellosis was diagnosed in 21
subjects, of whom only five recalled an accidental
exposure. Clinical manifestations were mild, and
only one patient presented a complication. After
antimicrobial therapy, initially symptomatic
patients either experienced clinical remission or
had mild persistent symptoms. This is the first
study reporting infection by B. abortus S19 among
workers from vaccine-manufacturing plants,
which in many cases was acquired from unnoticed
exposures. Measures to improve the safety of
B. abortus S19 handling should be implemented.