PERSONAL DE APOYO
SARI Luciana MarÍa
artículos
Título:
Expression of β‐NGF and high‐affinity NGF receptor (TrKA) in llama ( Lama glama ) male reproductive tract and spermatozoa
Autor/es:
SARI, LUCIANA M.; ZAMPINI, RENATO; ARGAÑARAZ, MARTIN E.; CARRETERO, MARÍA I.; FUMUSO, FERNANDA G.; BARRAZA, DANIELA E.; RATTO, MARCELO; APICHELA, SILVANA A.
Revista:
MOLECULAR REPRODUCTION AND DEVELOPMENT
Editorial:
WILEY-LISS, DIV JOHN WILEY & SONS INC
Referencias:
Año: 2018 vol. 85 p. 934 - 944
ISSN:
1040-452X
Resumen:
β‐Nerve growth factor (β‐NGF) is a seminal plasma element, responsible for inducing ovulation in camelids. The main organ of β‐NGF production remains nondescript. The aims of this study were to (a) characterize gene expression and protein localization of β‐NGF and its main receptor tyrosine kinase receptor A (TrKA) in the llama male reproductive tract, and (b) determine whether the seminal β‐NGF interacts with ejaculated sperm by localizing β‐NGF and TrKA in epididymal, ejaculated, and acrosome‐reacted (AR) sperms and, additionally, by identifying β‐NGF presence in sperm‐adsorbed proteins (SAP). Both β‐NGF and TrkA transcripts are widely expressed along the male reproductive tract, with a higher expression level of β‐NGF at prostate (p
