An improved approach to estimate the avidity index of immunoglobulins: Evaluation of the method using IgG anti- Toxoplasma gondii

GARCÍA, VALERIA S.; PEVERENGO, LUZ; PERETTI, LEANDRO E.; GONZÁLEZ, VERÓNICA D.G.; GUGLIOTTA, LUIS M.; DALLA FONTANA, MARIA L.; MARCIPAR, IVÁN S.; LAGIER, CLAUDIA M.

JOURNAL OF IMMUNOLOGICAL METHODS

ELSEVIER SCIENCE BV

Año: 2018

0022-1759

In this work we used an alternative display and analysis of the avidity data which allowed obtaining reliable IgG-AI values. As a major improvement, our AUAC approach avoids the difficulties to determine the E-P (titration curve method), and IgG quantitation (OD method). This is therefore a simple method for AI calculations when reliable values are needed, such as when diagnosing toxoplasmosis stages in pregnant women.