Perfusion pressure and renal blood flow: their relationship and differences

MUSSO, CARLOS GUIDO; VILAS, MANUEL; JAUREGUI, JOSE R.

Electron J Biomed

MJ Coma MD, PhD. Unidad de Investigación. Hospital General Yagüe

Año: 2014

The concepts of renal perfusion pressure (RPP) and renal blood flow (RBF) are usually confused, but although they are intimately related, they are not strictly the same. RPP originates from the minute cardiac volume and is, therefore, the cause of RBF, which generates glomerular filtration and as a consequence, also induces the urinary flow.On the other hand, whereas RPP can be subject to fluctuations, the same happens to RBF though at a much lower level due to the existence of physiological mechanisms, such as self-regulation of the flow and tubule-glomerular feed-back. We conclude that there is a dependence of the RBF in relation with RPP, with the former acting as the final responsible of the glomerular filtration.