How safe is Moderate Alcohol Consumption in Overweight and Obese Individuals?

SOOKOIAN S; PIROLA CJ

GASTROENTEROLOGY

W B SAUNDERS CO-ELSEVIER INC

Lugar: Philadelphia; Año: 2016 vol. 150 p. 1698 - 1703

0016-5085

The prevalence of nonalcoholic fatty liver disease (NAFLD) has reached global epidemicproportions, paralleling that of the increasing trends in the prevalence of obesity and type 2diabetes (T2D). In fact, obesity is one of the most frequently associated comorbidities of NAFLD, and furthermore, NAFLD and obesity integrate the myriad of risk factors for cardiovasculardisease (CVD) clustered in the metabolic syndrome (MetS).By definition, NAFLD is characterized by abnormal liver fat accumulation in the absence ofsignificant alcohol consumption and other causes of secondary hepatic steatosis. Oncediagnosed, the treatment of NAFLD is complex and often requires pharmacological interventionto control associated-risk factors, and or/ lifestyle modifications.Conflicting results on whether social or moderate alcohol consumption (MAC) is detrimental orbeneficial leave physicians uncertain as to whether or not to apply tight restrictions or allow lowlevels of social alcohol use for potential health benefit.