INVESTIGADORES
RODRIGUEZ Enrique Marcelo
artículos
Título:
Endocrine disruption in crustaceans due to pollutants: a review.
Autor/es:
RODRÍGUEZ, E.M.; MEDESANI, D.A.; FINGERMAN, M.
Revista:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY
Editorial:
Elsevier
Referencias:
Lugar: Amsterdam; Año: 2007 vol. 146 p. 661 - 671
ISSN:
1095-6433
Resumen:
The main
endocrine-regulated processes of crustaceans have been reviewed in relation to
the effects of endocrine-disrupting compounds (EDCs). Molting has been shown to
be inhibited by several organic pollutants, such as xenoestrogens and related
compounds, as well as by some pesticides. Most of these disrupters are thought
to interfere with ecdysone at target tissues, although only for a fewhas this
action been de2monstrated in vitro. The heavy metal cadmium appears to inhibit
some ecdysone secretion. Juvenoid compounds have also been shown to
inhibitmolting, likely by interfering with the stimulatory effect of methyl
farnesoate. A molt-promoting effect of emamectin benzoate, a pesticide, has
also been reported. As for reproduction, a variety of organic compounds,
including xenoestrogens, juvenoids and ecdysteroids, has produced abnormal
development of male and female secondary sexual characters, as well as
alteration of the sex ratio. Cadmium and copper have been shown to interfere
with hormones that stimulate reproduction, such as methyl farnesoate, as well
as with secretion of the gonad inhibiting hormone, therefore affecting, for
example, ovarian growth. Several heavy metals were able to produce
hyperglycemia in crustaceans during short times of exposure; while a
hypoglycemic response was noted after longer exposures, due to inhibition of
secretion of the crustacean hyperglycemic hormone. The ecological relevance of
EDCs on crustaceans is discussed, mainly in relation to the identification of
useful biomarkers and sentinel species. New experimental approaches are also
proposed.