INVESTIGADORES
FUNDIA Ariela Freya
artículos
Título:
Expression of common fragile sites in two Ceboidea species: Saimiri boliviensis and Alouatta caraya (Primates: Platyrrhini)
Autor/es:
ARIELA FUNDIA; MARÍA GOROSTIAGA; MARTA MUDRY
Revista:
GENETICS SELECTION EVOLUTION
Editorial:
BIOMED CENTRAL LTD
Referencias:
Lugar: París; Año: 2000 vol. 32 p. 87 - 97
ISSN:
0999-193X
Resumen:
Fragile sites are points of preferential breakage that may be involved in chromosome rearrangements. Induction of common fragile sites (c-fra) and spontaneous breakage were analyzed in two New World Monkeys species: Saimiri boliviensis (SBO) and Alouatta caraya (ACA). Spontaneous chromosome aberrations were analyzed on untreated lymphocyte cultures with Brögger´s formula (1977). SBO presented a low level of spontaneous breakage, while higher frequencies were detected in ACA in which bands 1q23; 2q13 and 11q19 were significantly affected (p