INVESTIGADORES
FUNDIA Ariela Freya
artículos
Título:
Evidence of chromosome instability in chronic pancreatitis
Autor/es:
COTTLIAR AS; FUNDIA AF; MORÁN C; SOSA E; GELDERN P; GÓMEZ JC; CHOPITA N; SLAVUTSKY IR
Revista:
JOURNAL OF EXPERIMENTAL AND CLINICAL CANCER RESEARCH
Editorial:
BIOMED CENTRAL LTD
Referencias:
Año: 2000 vol. 19 p. 513 - 517
ISSN:
1756-9966
Resumen:
In the current study we analyzed chromosome instability on peripheral blood lymphocytes cultured from 7 untreated patients with chronic pancreatitis (CP) by assessing telomeric associations (TAS), chromosome aberrations (CA) and sister chromatid exchanges (SCE). Seven healthy individuals were also analyzed. Mean frequencies of TAS were significantly higher in CP patients (X +/- SE: 11.00 +/- 2.37) compared to controls (1.00 +/- 0.30) (p