INVESTIGADORES
PIRO Oscar Enrique
artículos
Título:
Asymmetric construction of substituted pyrrolidines via 1,3-dipolar cycloaddition of azomethine ylides and chiral acrylates derived from biomass
Autor/es:
D. F. LLOMPART; A. M. SAROTTI; V. CORNE; A. G. SUÁREZ; R. A. SPANEVELLO; G. A. ECHEVERRÍA; O. E. PIRO ; E. E. CASTELLANO
Revista:
TETRAHEDRON LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2014 vol. 15 p. 2394 - 2397
ISSN:
0040-4039
Resumen:
N-Metallated azomethine ylides were generated by the reaction of arylidene glycine imines with AgOAc and triethylamine. These azomethine ylides undergo cycloaddition to chiral acrylamides with excellent diastereoselectivity. The configuration of two of the cycloadducts was confirmed by X-ray crystallography.
