Low Temperature Crystal Structure of Natural Diosgenone

O.E. PIRO; E. E. CASTELLANO; G. E. TOBÓN-ZAPATA; S. BLAIR-TRUJILLO; E. J. BARAN

Z. Naturforsch. C

Verlag

Año: 2002 vol. 57 p. 947 - 950

The molecular structure of diosgenone, a natural steroidal sapogenin, closely related to diosgenin and isolated from Solanum nudum, was solved by single crystal X-ray diffractometry at 120 K and refined by full-matrix least-squares to an agreement factor, R1 = 0.054. It crystallizes in the monoclinic space group P21, with a = 15.1870(4) A, b = 7.2710(2) A, c = 21.2840(6) A, beta = 99.251(1)º, and four molecules in the unit cell (Z = 4). The results constitute the first structural report on a steroidal sapogenin from the diosgenin group.