INQUISAL 20936
INSTITUTO DE QUIMICA DE SAN LUIS "DR. ROBERTO ANTONIO OLSINA"
Unidad Ejecutora - UE
artículos
Título:
Diuretic activity of aqueous extract and betulin from Colliguaja integerrima Gillies & Hook (Euphorbiaceae) in rats.
Autor/es:
MARÍA E. ALVAREZ; RAÚL GIL; GIMENA ACOSTA; ROBERTO SAAD; EDUARDO BORKOWSKI; ALEJANDRA O. MARÍA
Revista:
PHARMACEUTICAL BIOLOGY
Referencias:
Año: 2008
ISSN:
1388-0209
Resumen:
Five known compounds were isolated from the aerial parts of Colliguaja integerrima Gillies & Hook (Euphorbiaceae). A pharmacological evaluation of the diuretic activity of the plant was carried out in isotonic saline loaded rats. The data reported in the present work indicate that the aqueous extract of de aerial parts from C. integerrima showed a moderate diuretic activity. The urinary levels of sodium and potassium are increased by treatment with C. integerima aqueous extract. This activity could be due, in part, to the presence of betulin isolated as the major metabolite of C. integerrima.
