Pertussis Across the Globe: Recent Epidemiologic Trends From 2000-2013

TANT T; DALBY T; FORSYTH K; HALPERIN SA; HEININGER U; HOZBOR D; PLOTKIN S; ULLOA-GUTIERREZ R; VON KÖNIG CH

PEDIATRIC INFECTIOUS DISEASE JOURNAL

LIPPINCOTT WILLIAMS & WILKINS

Lugar: Philadelphia; Año: 2015

0891-3668

<!-- /* Font Definitions */@font-face{font-family:Arial;panose-1:2 11 6 4 2 2 2 2 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:-536859905 -1073711037 9 0 511 0;}@font-face{font-family:Arial;panose-1:2 11 6 4 2 2 2 2 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:-536859905 -1073711037 9 0 511 0;}@font-face{font-family:Calibri;panose-1:2 15 5 2 2 2 4 3 2 4;mso-font-charset:0;mso-generic-font-family:auto;mso-font-pitch:variable;mso-font-signature:-520092929 1073786111 9 0 415 0;}@font-face{font-family:"MS ??";panose-1:0 0 0 0 0 0 0 0 0 0;mso-font-alt:"MS Mincho";mso-font-charset:128;mso-generic-font-family:auto;mso-font-format:other;mso-font-pitch:variable;mso-font-signature:1 134676480 16 0 131072 0;} /* Style Definitions */p.MsoNormal, li.MsoNormal, div.MsoNormal{mso-style-unhide:no;mso-style-qformat:yes;mso-style-parent:"";margin-top:0cm;margin-right:0cm;margin-bottom:10.0pt;margin-left:0cm;line-height:115%;mso-pagination:widow-orphan;font-size:11.0pt;font-family:Calibri;mso-fareast-font-family:"MS ??";mso-bidi-font-family:"Times New Roman";mso-ansi-language:EN-US;mso-fareast-language:JA;}.MsoChpDefault{mso-style-type:export-only;mso-default-props:yes;font-size:11.0pt;mso-ansi-font-size:11.0pt;mso-bidi-font-size:11.0pt;font-family:Calibri;mso-ascii-font-family:Calibri;mso-fareast-font-family:"MS ??";mso-hansi-font-family:Calibri;mso-ansi-language:DE;mso-fareast-language:DE;}@page WordSection1{size:612.0pt 792.0pt;margin:72.0pt 90.0pt 72.0pt 90.0pt;mso-header-margin:36.0pt;mso-footer-margin:36.0pt;mso-paper-source:0;}div.WordSection1{page:WordSection1;}-->Summary Pertussishas reemerged as a problem across the world. To better understand the nature ofthe resurgence, we reviewed recent epidemiological data and report diseasetrends from across the world. Published epidemiologic data from January 2000 toJuly 2013 were obtained via PubMed searches and open-access websites. Data onvaccine coverage and reported pertussis cases from 2000 through 2012 from the 6World Health Organization (WHO) regions were also reviewed. Findings areconfounded by the lack of systematic and comparable observations in many areasof the world, but also by the cyclicity of pertussis with peaks occurring every3 to 5 years. Nevertheless, it appears that pertussis incidence has increasedin school-age children in North America and western Europe, where acellularpertussis vaccines are used, but an increase has also occurred in somecountries that use whole-cell vaccines. Worldwide, pertussis remains a serious healthconcern, especially for infants, who bear the greatest disease burden. Factorsthat may contribute to the resurgence include lack of booster immunizations,low vaccine coverage, improved diagnostic methods, and genetic changes in the organism.To better understand the epidemiology of pertussis and optimize diseasecontrol, it is essential to improve surveillance worldwide, irrespective ofpertussis vaccine types and schedules used in each country.