Effect of vitamin D nutritional satatus on muscle function and strength in healthy women aged over sixty-five years

MASTAGLIA SILVINA, SEIJO MARIANA, MUZIO DIANA, SOMOZA JULIA, OLIVERI BEATRIZ

JOURNAL OF NUTRITION HEALTH & AGING

SPRINGER FRANCE

Año: 2010 p. 1 - 6

1279-7707

Vitamin D insufficiency is common in elderly adults, and leads to secondary hyperparathyroidism, bone loss, muscle weakness, and osteoporotic fractures. Objective: To evaluate the relation between vitamin D nutritional status and muscle function and muscle strength in women aged over 65 years. Methods: Fifty-four postmenopausal women from Buenos Aires (latitude 34° S), average age (X±DS) 71±4, were included in the study. Determinations of serum calcium, phosphate, 25 hydroxyvitamin D (25OHD), intact parathormone (iPTH) and calciuria / creatininuria ratio in 24-hour urine samples were performed. Muscle function was assessed by means of walking-speed test, standing balance, and sit-to-stand tests. Lower extremity muscle strength was determined using a manual dynamometer. Results: 25OHD levels ≥20ng/ml were found to be associated with better lower extremity muscle function and strength. Forty- six % of participants had 25OHD levels ≥20ng/ml. Women with 25OHD levels ≥20ng/ml scored higher on the muscle function tests (11.2±0.9 vs.10.0±2.1; p