INVESTIGADORES
MBAYED Viviana Andrea
artículos
Título:
Phylogenetic analysis of the hepatitis B virus (HBV) genotype F including Argentine isolates.
Autor/es:
MBAYED, V.; BARBINI, L.; LÓPEZ, J.; CAMPOS, R.
Revista:
ARCHIVES OF VIROLOGY
Editorial:
Springer
Referencias:
Lugar: New York; Año: 2001 vol. 146 p. 1803 - 1810
ISSN:
0304-8608
Resumen:
Seven human hepatitis B virus (HBV) genotypes have been described.Genotype F, indigenous to the Americas, is the most diverging group. Our in-depthanalysis of the genetic distances of this genotype included ten Argentine samples.Phylogenetic analysis on the small (S) gene of the surface antigen showed fourdifferent clusters within genotype F, which were associated with a well-definedgeographical origin. Even closely connected sequences sharing a common ancestorhad shown some characteristics or markers indicating geographical differentiation.Nucleotide sequences and amino acids translated according to thepolymerase open reading frame (P-ORF), rather than S-ORF, yielded a morediscriminating analysis.
