INVESTIGADORES
D'ACCORSO Norma Beatriz
artículos
Título:
Synthesis of imidazo[2,1-b]thiazoles linked to an unprotected carbohydrate moiety
Autor/es:
BARRADAS JOSÉ S.; ERREA, MARÍA I.; D'ACCORSO NORMA B.
Revista:
CARBOHYDRATE RESEARCH
Editorial:
ELSEVIER SCI LTD
Referencias:
Lugar: Amsterdam; Año: 2012 vol. 355 p. 79 - 86
ISSN:
0008-6215
Resumen:
Two series of imidazo[2,1-b]thiazoles substituted on C-3 or C-5 with an unprotected carbohydrate moiety were synthesized. Different protective groups for position 3 of the carbohydrate moiety were tested (acetyl, tert-butyldimethylsilyl (TBDMS) and p-methoxybenzyl (PMB)) and the latter turn out to be the best strategy to obtain the desired products. Full deprotection of the carbohydrate was performed successfully in only one step.
