INVESTIGADORES
GIORDANO Walter Fabian
artículos
Título:
Aeration affects acetate destination in Gibberella fujikuroi
Autor/es:
GIORDANO, W. AND DOMENECH, C. E.
Revista:
FEMS MICROBIOLOGY LETTERS
Editorial:
Elsevier
Referencias:
Año: 1999 vol. 180 p. 111 - 116
ISSN:
0378-1097
Resumen:
Gibberellins, fatty acids and the polyketides bikaverin and fusarin C are synthesized from a common precursor, acetyl-CoA. The production of these compounds in Gibberella fujikuroi wasstrongly influenced by aeration, determined by the air/médium ratio in shaken batch cultures. Higher aeration resulted in increased growth and the production of bikaverin and gibberellins. Low aeration stimulated fatty acid and fusarin C production. Feeding experiments with labeled leucine or acetate resulted in different proportions of labeled palmitic acid and bikaverin, indicating that these compounds are synthesized from independent acetate pools.
