INVESTIGADORES
LARRABIDE Ignacio
artículos
Título:
Change in aneurysmal flow pulsatility after flow diverter treatment
Autor/es:
I. LARRABIDE; A. J. GEERS; H. MORALES; P. BIJLENGA; D. RUFENACHT
Revista:
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2014
ISSN:
0895-6111
Resumen:
Motivation: Treatment of intracranial aneurysms with
flow diverters (FDs) has recently become an attractive alternative.
Although considerable effort has been devoted to understand their
effects on the time-averaged or peak systolic flow field, no previous
study has analyzed the variability of FD-induced flow reduction along
the cardiac cycle.
Methods: Fourteen saccular
aneurysms, candidates for FD treatment because of their morphology,
located on the internal carotid artery were virtually treated with FDs
and pre- and post-treatment blood flow was simulated with CFD
techniques. Common hemodynamic variables were recorded at each time step
of the cardiac cycle and differences between the untreated and treated
models were assessed.
Results: Flow pulsatility,
expressed by the pulsatility index (PI) of the velocity, significantly
increased (36.0%; range: 14.6% to 88.3%) after FD treatment. Peak
systole velocity reduction was significantly smaller (30.5%; range:
19.6% to 51.0%) than time-averaged velocity reduction (43.0%; range:
29.1% to 69.8%). No changes were observed in the aneurysmal pressure.
Conclusions:
FD-induced flow reduction varies considerably during the cardiac cycle.
FD treatment significantly increased the flow pulsatility in the
aneurysm.