INVESTIGADORES
MESSINA Paula Veronica
artículos
Título:
A Potentiometric and Spectroscopy study on the interaction between Human Immunoglobulin G and Sodium perfluorooctanoate in aqueous solution
Autor/es:
P.V. MESSINA; G. PRIETO; J. SABIN; E. BLANCO; C. VARELA; V. DODERO; J.M. RUSO; F. SARMIENTO
Revista:
MACROMOLECULAR SYMPOSIA
Editorial:
Wiley Inter Science
Referencias:
Año: 2007 vol. 251 p. 103 - 111
ISSN:
1022-1360
Resumen:
The interaction between human immunoglobulin G (IgG) and sodium perfluorooctanate (SPFO) has been characterized by a combination of UV-vis and UV-CD spectroscopies and ion selective electrodes. The study determined that there were true specific unions between SPFO and IgG. The conformational changes at the bulk solution, induced by SPFO, were well characterized by UV-vis and UV-CD spectroscopies. Chemical and thermal unfolding were analysed and the thermodynamic parameters were determined.
