INVESTIGADORES
OZU Marcelo
artículos
Título:
From Membrane Pores to Aquaporins: 50 Years Measuring Water Fluxes
Autor/es:
MARIO PARISI; RICARDO A. DORR; MARCELO OZU; ROXANA TORIANO
Revista:
JOURNAL OF BIOLOGICAL PHYSICS
Editorial:
SPRINGER
Referencias:
Año: 2007 vol. 33 p. 331 - 343
ISSN:
0092-0606
Resumen:
This review focuses on studies of water movement across biological membranes performed over the last 50 years. Different scientific approaches had tried to elucidate such intriguing mechanism, from hypotheses emphasizing the role of the lipid bilayer to the cloning of aquaporins, the ubiquitous proteins described as specific water channels. Pioneering and clarifying biophysical work are reviewed beside results obtained with the help of recent sophisticated techniques, to conclude that great advances in the subject live together with old questions without definitive answers.
