INVESTIGADORES
MAZZOLINI RIZZO Guillermo Daniel
artículos
Título:
Cancer immunotherapy. Importance of overcoming immune suppression
Autor/es:
MALVICINI M; PUCHULO G; MATAR P; MAZZOLINI G
Revista:
MEDICINA (BUENOS AIRES)
Editorial:
MEDICINA (BUENOS AIRES)
Referencias:
Lugar: Buenos Aires; Año: 2010 p. 565 - 570
ISSN:
0025-7680
Resumen:
Increasing evidence indicates that the immune system is involved in the control of tumor progression. Effective antitumor immune response depends on the interaction between several components of the immune system, including antigen-presenting cells and different T cell subsets. However, tumor cells develop a number of mechanisms to escape recognition and elimination by the immune system. In this review we discuss these mechanisms and address possible therapeutic approaches to overcome the immune suppression generated by tumors.