INVESTIGADORES
SALOMON Oscar Daniel
artículos
Título:
Cost-effectiveness of prevention strategies for American tegumentary leishmaniasis in Argentina
Autor/es:
ORELLANO, PW; VAZQUEZ N; SALOMON OD
Revista:
CADERNOS DE SAúDE PúBLICA
Editorial:
CADERNOS SAUDE PUBLICA
Referencias:
Lugar: Rio de Janeiro; Año: 2013 vol. 29 p. 2459 - 2472
ISSN:
0102-311X
Resumen:
The aim of this study was to estimate the cost-effectiveness
of reducing tegumentary leishmaniasis
transmission using insecticide-impregnated
clothing and curtains, and implementing training
programs for early diagnosis. A societal perspective
was adopted, with outcomes assessed in
terms of costs per disability adjusted life years
(DALY). Simulation was structured as a Markov
model and costs were expressed in American dollars
(US$). The incremental cost-effectiveness
ratio of each strategy was calculated. One-way
and multivariate sensitivity analyses were performed.
The incremental cost-effectiveness ratio
for early diagnosis strategy was estimated at US$
156.46 per DALY averted, while that of prevention
of transmission with insecticide-impregnated
curtains and clothing was US$ 13,155.52 per
DALY averted. Both strategies were more sensitive
to the natural incidence of leishmaniasis, to
the effectiveness of mucocutaneous leishmaniasis
treatment and to the cost of each strategy. Prevention
of vectorial transmission and early diagnosis
have proved to be cost-effective measures.