INVESTIGADORES
MBAYED Viviana Andrea
artículos
Título:
Analysis of the circulation of hepatitis A virus in Argentina since vaccine introduction
Autor/es:
BLANCO FERNÁNDEZ, M.D.; TORRES, C.; RIVIELLO LÓPEZ, G.; POMA, H.; RAJAL, V.; NATES, S.; CISTERNA , D; CAMPOS, R.; MBAYED, V.
Revista:
CLINICAL MICROBIOLOGY AND INFECTION
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Lugar: Londres; Año: 2012 p. 548 - 551
ISSN:
1198-743X
Resumen:
Hepatitis A virus (HAV) has shown intermediate endemicity in Argentina,but its incidence decreased since vaccine introduction in 2005.Environmental surveillance was conducted in five rivers from Argentinafrom 2005 to 2012, complementing clinical information. HAV detectiondecreased since 2005, although its circulation continues, maintaining viraldiversity but not undergoing antigenic drift. Most sequences belonged tosubgenotype IA closely related to Argentinean clinical sequences, but onebelonged to proposed subgenotype IC, previously undetected in thecountry. Environmental surveillance might contribute to monitor singledosevaccination schedule, representing not only strains causing diseasebut also the circulating population, and show viral introductions.
