Characterisation of interstitial cells of Cajal in the bowel of the cattle

MÁRQUEZ S; GALOTTA J; PORTIANSKY E; BARBEITO CG

VETERINARY RESEARCH COMMUNICATIONS

Springer

Lugar: Edimburgo; Año: 2006 vol. 30 p. 221 - 229

0165-7380

Interstitial Cajal Cells (ICC) have been described in the gastointestinal tract of different mammals. In the present study ICC were identified in the jejunum of Bos taurus using poluçyclonal anti-cKit antibodies in immunohistochemical assays. Vimentin and desmin intermediate filaments were also determined using monoclonal antibodies. ICC were found in the tunica muscularis either in a palisade distribution pattern between the outer the muscular layers or freely distributed in cluster in the longitudinal layer. Morphometric studies determined that ICC have a fusiform shape presenting cytoplasmatic prolongations ICC were positive to cKit and vimentin but negative to desmin. We have described for the first time the presence of ICC in ruminants. As observed in other mammals, bovine ICC were associated with the myenteric plexus neverthelesss the presence of widespread ICC in the longitudinal muscular layer of the jejunum differs from previously described studies of other mammals