CEFOBI   05405
CENTRO DE ESTUDIOS FOTOSINTETICOS Y BIOQUIMICOS
Unidad Ejecutora - UE
artículos
Título:
Flavonoids: biosynthesis, biological functions, and biotechnological applications
Autor/es:
FALCONE L.; SEBASTIÁN P. RIUS; PAULA CASATI
Revista:
FRONTIERS IN BIOSCIENCE-LANDMARK
Editorial:
FRONTIERS IN BIOSCIENCE INC
Referencias:
Lugar: Albertson, NY, USA; Año: 2012 vol. 3 p. 222 - 222
ISSN:
1093-9946
Resumen:
Flavonoids are widely distributed secondary metabolites with different
metabolic functions in plants. The elucidation of the biosynthetic
pathways, as well as their regulation by MYB, basic helix-loop-helix
(bHLH), and WD40-type transcription factors, has allowed metabolic
engineering of plants through the manipulation of the different final
products with valuable applications. The present review describes the
regulation of flavonoid biosynthesis, as well as the biological
functions of flavonoids in plants, such as in defense against UV-B
radiation and pathogen infection, nodulation, and pollen fertility. In
addition, we discuss different strategies and achievements through the
genetic engineering of flavonoid biosynthesis with implication in the
industry and the combinatorial biosynthesis in microorganisms by the
reconstruction of the pathway to obtain high amounts of specific
compounds..