INVESTIGADORES
GONZALEZ graciela alicia
artículos
Título:
Mass transport effect of mesoscopic domains in the amperometric
Autor/es:
GRACIELA GONZÁLEZ, GRACIELA PRIANO, MAURICIO GÜNTHER, FERNANDO BATTAGLINI
Revista:
SENSORS AND ACTUATORS B-CHEMICAL
Editorial:
ELSEVIER
Referencias:
Año: 2010 vol. 144 p. 349 - 353
ISSN:
0925-4005
Resumen:
We report the numerical simulation of an electrochemical system compromising a mesoporous material
placed at a close distance of a working electrode. The effect of mesoscopic domains to the amperometric
response of an electroactive species by applying a cyclic voltammetry is simulated to establish
the in.uence of different parameters on the sensitivity of this system to detect molecules able to block
the pores. Alumina membranes were chosen as mesoporous material; they were modi.ed with antihorseradish
peroxidase as model system to test the behavior predicted by the simulation. The label-free
assembled electrochemical system shows a reproducible behavior and it is able to detect a 10 nMprotein
concentration.