INVESTIGADORES
DI CONZA Jose Alejandro
artículos
Título:
Dos aislamientos de Salmonella Infantis multirresistente se comportan como hipoinvasivos pero con elevada proliferación intracelular
Autor/es:
DI CONZA JOSÉ; MOLLERACH MARTA; GUTKIND GABRIEL; AYALA JUAN
Revista:
REVISTA ARGENTINA DE MICROBIOLOGÃA
Editorial:
ASOCIACION ARGENTINA MICROBIOLOGIA
Referencias:
Lugar: Buenos Aires; Año: 2012 vol. 44 p. 69 - 74
ISSN:
0325-7541
Resumen:
Two multidrug-resistant Salmonella Infantis isolates behave like low-invasive but high intracellular proliferation. In this work we investigated plasmid-encoded virulence factors in two Salmonella Infantis isolates carrying multiresistance plasmids. In addition, we studied the ability of invasion and proliferation in non-phagocytic cells. None of them showed the typical determinants of virulence plasmid (spv operon). The invasion assays of S. Infantis isolates on eukaryotic cells showed a decreased ability to invade but they remain and proliferate into the cytoplasm regardless of using a permissive (HeLa) or non-permissive (NRK) cell line. Finally, there were not microscopic evidences suggesting a bactericidal effect of these eukaryotic cell lines on isolates tested.
