INVESTIGADORES
GRASSO daniel Hector
artículos
Título:
Autophagy in pancreatic cancer.
Autor/es:
GRASSO, DANIEL; GARCIA, MARIA NOE; IOVANNA, JUAN L.
Revista:
International Journal of Cell Biology
Editorial:
Hindawi Publishing Corporation
Referencias:
Lugar: New York; Año: 2012 vol. 2012 p. 760498 - 760498
ISSN:
1687-8884
Resumen:
Pancreatic adenocarcinoma (PDAC) is a devastating disease with an extremely poor life expectancy and no effective treatment. Autophagy is a process of degradation of cytoplasmic component capable of recycling cellular components or eliminate specific targets. The presence of autophagy in PDAC has been demonstrated. However, the implicated cellular pathways are not fully understood and, more importantly, the role of autophagy in PDAC is matter of intensive debate. This review summarizes recently published data in an attempt to clarify the importance of autophagy in this disease and try to reconcile apparently contradictory results.
