INVESTIGADORES
BORDONI Andrea Veronica
artículos
Título:
Facile synthesis of methyl alpha- and beta-D-[6-3H]galactofuranosides from D-galacturonic acid. Substrates for the detection of galactofuranosidases.
Autor/es:
A. BORDONI; C. LIMA; K. MARIÑO; R. M. DE LEDERKREMER; C. MARINO
Revista:
CARBOHYDRATE RESEARCH
Editorial:
ELSEVIER
Referencias:
Lugar: Nueva York; Año: 2008 vol. 343 p. 1863 - 1869
ISSN:
0008-6215
Resumen:
Galactofuranose metabolism is a good target for the development of novel chemotherapeutic agents for the treatment of some microbial infections. A simple procedure for the synthesis of methyl (methyl a,b-D-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases.a,b-D-galactopyranosid)uronate followed by NaB3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases.3H4 reduction gave a straightforward access to radiolabeled substrates for galactofuranosidases. 2008 Elsevier Ltd. All rights reserved.2008 Elsevier Ltd. All rights reserved.