Permethylated β-cyclodextrin in liquid poly(oxyethylene) as a stationary phase for capillary gas chromatography

JAIVER OSORIO GRISALES, PABLO J. LEBED, SONIA KEUNCHKARIAN, FRANCISCO R. GONZÁLEZ, CECILIA B. CASTELLS*

JOURNAL OF CHROMATOGRAPHY - A

Elsevier

Año: 2009 vol. 1216 p. 6844 - 6851

0021-9673

11 AbstractAbstract 12 This paper reports the study of poly(oxyethylene) as a solvent for heptakis(2,3,6-tri-O-methyl)-b-cyclodextrin (PM-This paper reports the study of poly(oxyethylene) as a solvent for heptakis(2,3,6-tri-O-methyl)-b-cyclodextrin (PM- 13 b-CD) and the potential of these mixtures for constructing enantioselective gas chromatography columns.b-CD) and the potential of these mixtures for constructing enantioselective gas chromatography columns. 14 Enantioseparations of volatile racemic mixtures using capillaries coated with 10 to 50% PM-b-CD diluted inEnantioseparations of volatile racemic mixtures using capillaries coated with 10 to 50% PM-b-CD diluted in 15 Carbowax 20M were evaluated. The influence of the polymer type on retention, separation and reproducibilityCarbowax 20M were evaluated. The influence of the polymer type on retention, separation and reproducibility 16 over a period of time is critically discussed. The poly(oxyethylene)-based columns were also compared toover a period of time is critically discussed. The poly(oxyethylene)-based columns were also compared to 17 columns prepared by dilution of PM-b-CD in two polysiloxanes, SE-30 and SE-54, at several temperatures.columns prepared by dilution of PM-b-CD in two polysiloxanes, SE-30 and SE-54, at several temperatures. 18 Finally, we evaluated a new stationary phase prepared by crosslinking the chiral selector to the poly(oxyethylene)Finally, we evaluated a new stationary phase prepared by crosslinking the chiral selector to the poly(oxyethylene) 19 matrix.matrix.