Bactericidal effects of copper-polypyrrole composites modified with silver nanoparticles against Gram-positive and Gram-negative bacteria

MARUCCI, PATRICIA; SICA, MARIA; BRUGNONI, LORENA; GONZÁLEZ, MARÍA BELÉN

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY

SERBIAN CHEMICAL SOC

Lugar: Belgrado; Año: 2023 vol. 88 p. 889 - 904

0352-5139

The aim of this research is to study the bactericidal effects of copper–polypyrrole (PPy) composites deposited onto 316L stainless steel (SS) modi­fied with silver nanopar­ticles (Np). The antimicrobial properties were eval­uated against twenty-four strains of Gram-positive and Gram-negative bacteria. Among the twenty-four strains studied, isolates included reference strains (Escherichia coli ATCC 25922, Escherichia coli 0157:H7 EDL 933, Sta­phylo­coccus aureus ATCC 25923 and Listeria monocytogenes ATCC 7644), as well as strains iso­lated from food and clinical samples. The antimicrobial activity of the compo­sites demonstrated that all PPy-modified films had antibacterial properties. Notably, Cu-PPyAgNp500 exhibited the strongest inhibitory activity against both Gram-negative and Gram-positive bacteria. Surface modification of 316L SS with these films is a promising and viable alternative for the dev­elopment of novel antibacterial composites that can inhibit the growth of a sig­nificant num­ber of bacteria.