INVESTIGADORES
SÜLSEN valeria Patricia
artículos
Título:
Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract
Autor/es:
GORZALCZANY S; SÜLSEN V; REDKO F; VESCINA C; MUSCHIETTI L; MARTINO V; ACEVEDO C
Revista:
REVISTA BRASILEIRA DE FARMACOGNOSIA
Editorial:
Brazilian Society of Pharmacognosy
Referencias:
Lugar: Joao Pessoa, Brasil; Año: 2008 vol. 18 p. 16 - 20
ISSN:
0102-695X
Resumen:
The aqueous extract of the aerial parts of Lippia integrifolia has been assayed for its choleretic and antispasmodic effects. Doses of 250, 500 and 750 mg/kg administered orally in rats significantly increased the bile flow and the bile acid output. The extract also showed a significant reduction of the contractions induced by acetylcholine, CaCl2 and KCl on isolated rat jejunum. The total caffeoyl quinic acids derivatives content, expressed as chlorogenic acid was 0.10% w/v by spectrophotometric determination.