INVESTIGADORES
RADIVOY Gabriel Eduardo
artículos
Título:
Design and synthesis of unnatural coordination glycopolymer particles (CGPs): unleashing the potential of catechol-saccharide derivatives
Autor/es:
BIDEPLÁN-MOYANO, CELINA; LO FIEGO, MARCOS J.; CALMELS, JUAN JOSÉ; ALONSO, BELÉN; RADIVOY, GABRIEL; RUIZ-MOLINA, DANIEL; MANCEBO-ARACIL, JUAN; NADOR, FABIANA
Revista:
RSC Advances
Editorial:
Royal Society of Chemistry
Referencias:
Año: 2023 vol. 13 p. 27491 - 27500
Resumen:
Our study unveils an innovative methodology that merges catechols with mono- and disaccharides,yielding a diverse array of compounds. This strategic fusion achieves robust yields and introduces ligands with a dual nature: encompassing both the chelating attributes of catechols and the recognition capabilities of carbohydrates. This synergistic design led us to couple one of the novel ligands with an Fe(III) salt, resulting in the creation of Coordination Glycopolymer Particles (CGPs). These CGPs demonstrate remarkable qualities, boasting outstanding dispersion in both aqueous media and Phosphate Buffered Saline (PBS) solution (pH ∼7.4) at higher concentrations (0.26 mg mL−1). Displaying an average Z-size of approximately 55 nm and favourable polydispersity indices (