INVESTIGADORES
ETCHEVERRIA Analia Ines
artículos
Título:
Shiga toxin-producing Escherichia coli Factors involved in virulence and cattle colonization
Autor/es:
ETCHEVERRÍA, ANALÍA I.; PADOLA, NORA L.
Revista:
Virulence
Editorial:
Landes Bioscience
Referencias:
Año: 2013 vol. 4 p. 1 - 7
ISSN:
2150-5608
Resumen:
Shiga toxin-producing Escherichia coli (STEC) causehemorrhagic colitis (HC) and hemolytic uremic syndrome(HUS) in humans. Outbreaks are linked to bovine food sources.STEC O157:H7 has been responsible for the most severeoutbreaks worldwide. However, non-O157 serotypes haveemerged as important enteric pathogens in several countries.The main virulence factor of STEC is the production of Shigatoxins 1 and 2. Additional virulence markers are a plasmidencodedenterohemolysin (ehxA), an autoagglutinatingadhesin (Saa), a catalase-peroxidase (katP), an extracellularserine protease (espP), a zinc metalloprotease (stcE), a subtilasecytotoxin (subAB), among others. Other virulence factors areintimin and adhesins that had a roll in the adherence of STECto bovine colon. This review focuses on the virulence traits ofSTEC and especially on those related to the adhesion to bovinecolon. The known of the interaction between STEC and thebovine host is crucial to develop strategies to control cattlecolonization.
